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Giro doping 2017

The Clinic is the only place on Cyclingnews where you can discuss doping-related issues. Ask questions, discuss positives or improvements to procedures.

Moderators: Irondan, Eshnar, Red Rick, Valv.Piti, Pricey_sky, Tonton, King Boonen

15 May 2017 22:11

GW-501516 is a PPARD agonist. PPARD commonly binds to fatty acids. If anyone is grouping it with "peptides", and you're going to have to define that group because "peptides" is pretty wide ranging, they need to learn some basic chemistry/biochemistry.

If you are going to group things on some mode of action-mimic class MK-677 should be grouped in your "peptides" group as it is a GHSR agonist, of which the majority are actually peptides (ghrelin being the endogenous agonist), even if MK-677 isn't.
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16 May 2017 11:21

Peptides are easily and routinely defined as short chains of amino acids linked by the peptide bonds.

Short bits of what would be protein in a longer form (Usually more than 50 AAs), used by biology for a variety of functions. (or created during digestion of proteins by the GI tract)


Any other definition is simply incorrect.
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16 May 2017 12:20

That's kind of my point ;)
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16 May 2017 13:15

Yep.

Just reinforcing it :)
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16 May 2017 16:26

Y'all boys know the show has started!
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16 May 2017 16:29

Once again we saw that Movistar riders loose at least 30W if the TT takes place outside of Spain.
Last edited by Mayomaniac on 16 May 2017 18:28, edited 1 time in total.
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Re:

16 May 2017 17:55

Mayomaniac wrote:Once again we saw that Movistar riders loose at leat 30W if the TT takes place outside of Spain.

Its odd isn't it?
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Re: Re:

16 May 2017 18:39

Valv.Piti wrote:
Mayomaniac wrote:Once again we saw that Movistar riders loose at leat 30W if the TT takes place outside of Spain.

Its odd isn't it?

Probably home field advantage and better logistics, a bit like the Italian gc riders in the early/mid 2000s. and some motopacing.
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17 May 2017 15:09

Monster performance by Omar Fraile.
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17 May 2017 20:31

Am I so jaded than when I saw the way TeeJay has been riding, he had the look of a completely clean rider?
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Re:

17 May 2017 20:40

Alpe d'Huez wrote:Am I so jaded than when I saw the way TeeJay has been riding, he had the look of a completely clean rider?


I've been thinking the same thing. If somehow true (he did lose 20 minutes today), is this where a line can be drawn? Or is it somewhere like 10 minutes, or 15 minutes that a clean rider could lose to a doped stage winner? Not calling Fraile a doper by any means, but TJVG is getting weaker with each pedal stroke. Some have suggested that he is saving something for future stages where he can get in a breakaway and finally get a GT stage win. That begs another question. If he is taking it 'easy,' how many 'easy' days or days where he paces himself to save energy, will be enough to have enough to be in a day long breakaway and win? This is assuming that he is riding clean NOW.
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Re:

17 May 2017 20:43

Alpe d'Huez wrote:Am I so jaded than when I saw the way TeeJay has been riding, he had the look of a completely clean rider?

I don't know about that, he was 5th on gc and one of the strongest riders in Romandie, probably the 2nd strongest right behind Richie and most of the early Giro stages weren't that hard to explain such a meltdown early on after a strong perfrmance in Romandie.
I still think something happened to him at the 2015 TdF when he had that massive meltdown, to me it looked like a bad blood bag.
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17 May 2017 22:33

Fraile looked completely bogus...fakery is strong in this one
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Re: Re:

17 May 2017 23:20

Mayomaniac wrote:
Alpe d'Huez wrote:Am I so jaded than when I saw the way TeeJay has been riding, he had the look of a completely clean rider?

I don't know about that, he was 5th on gc and one of the strongest riders in Romandie, probably the 2nd strongest right behind Richie and most of the early Giro stages weren't that hard to explain such a meltdown early on after a strong perfrmance in Romandie.
I still think something happened to him at the 2015 TdF when he had that massive meltdown, to me it looked like a bad blood bag.

Yeah, until that moment he certainly performed much better than in fact he is. Especially at the Dauphine already.

Since then, he's a complete shadow of his former self. He should at least be able to be 9th on gc.
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Re:

18 May 2017 04:38

Alpe d'Huez wrote:Am I so jaded than when I saw the way TeeJay has been riding, he had the look of a completely clean rider?


Been really wondering as to what is the problem. So glad this came up. Was thinking of starting a thread.
Maybe being a father of two kids has given him some perspective, is what came to mind. He has gone from having to hold up and wait for Cadel, to this.
People are bashing him, but ala Cunego, targeting one days and shorter stage races might be his future.
Falling off of a cliff like this makes me think he's gone cleans.
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Re: Re:

18 May 2017 07:40

staubsauger wrote:
Mayomaniac wrote:
Alpe d'Huez wrote:Am I so jaded than when I saw the way TeeJay has been riding, he had the look of a completely clean rider?

I don't know about that, he was 5th on gc and one of the strongest riders in Romandie, probably the 2nd strongest right behind Richie and most of the early Giro stages weren't that hard to explain such a meltdown early on after a strong perfrmance in Romandie.
I still think something happened to him at the 2015 TdF when he had that massive meltdown, to me it looked like a bad blood bag.

Yeah, until that moment he certainly performed much better than in fact he is. Especially at the Dauphine already.

Since then, he's a complete shadow of his former self. He should at least be able to be 9th on gc.

Yes, back then it looked like he had taken it to the next level, he was also getting Froome-thin.
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Re:

18 May 2017 15:59

70kmph wrote:Fraile looked completely bogus...fakery is strong in this one

My thoughts too.
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Re: Re:

18 May 2017 20:25

kingjr wrote:
70kmph wrote:Fraile looked completely bogus...fakery is strong in this one

My thoughts too.


Animate the break, get dropped, catch up and outsprint, while holding off the peloton on a fairly hilly stage -- what's so odd about that?
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Re: Re:

19 May 2017 00:59

Bolder wrote:
kingjr wrote:
70kmph wrote:Fraile looked completely bogus...fakery is strong in this one

My thoughts too.


Animate the break, get dropped, catch up and outsprint, while holding off the peloton on a fairly hilly stage -- what's so odd about that?

Nothing as long as you're on CERA and riding for team Gerolsteiner. If not, wel, well ...
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20 May 2017 15:35

That was fast.
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