I use a Thule hard case. I remove the rear derail and wrap the tubes in foam pipe insulation. Never had a problem. A buddy of mine has a softcase. Shifter was bent in about 30 degrees. Also the rear derail hanger pulled the screws from the frame. Frame threads were stripped. Big problems. Go hard.
I have read Lance rides with 175 cranks on his road bike. I have also been to the Trek factory in Waterloo WI, where they have his Tour De France road bikes in their showroom. I checked out the cranks, 175.
FYI,,,the cassette was a 11 X 21.