There are currently, no Professional Road racing events that take place in Sicily. There used to be a Professional road race held in Sicily. It was called the Giro Dell' Etna, which was held in the Years 1980-2004. It was a one day race, which attracted top pro riders and teams. Some notable winners include Francesco Moser, Rolf Sorensen, Mario Cipollini and Fillippo Pozzato.
Yes I stand corrected. The 2011 Giro will start ( 94 th edition ) in Turin on Saturday 7 th of May with a 22km team Time Trial. And end in Milan ( with an individual Time Trial ). The rest of the stages have Yet to be revealed. But it is rumored that there will be a stage in Sicily to tie in with the 150 th anniversary theme ( unification of Italy ) where Garibaldi landed with a 1000 troops to launch a campaign, that would eventually lead to the unification of Italy.