I found a video about doping, "Doping in Sports: Personal, Cultural and Athletic Impact". It's from an event in San Fransisco, August 2012, where three proffessors talks about doping. There's also a panel discussion. I don't know if this has been posted before.
Here's the summary from the site:
I haven't seen the whole thing yet, only snippets (well, 1 hour I guess). And I doubt there's anything new for the regular clinic posters. But I thought I should share anyway:
http://fora.tv/2012/08/20/Doping_in_Sports_Personal_Cultural_and_Athletic_Impact
It's a pity we're not able to hear the questions from the audience during the presentations. It's also annoying that we don't see what the audience are seeing when the proffessors are pointing at specific parts of their power point charts (we only see the charts as a fixed graphic). The video seems to be downloadable (worked for me).
EDIT:
The original link seems to be down but here is the Youtube link:
https://www.youtube.com/watch?v=aTjpgidjgWE
Overview of the first 35 minutes or so (I will post more headlines later). Times are approximate!
03:46 Kate Scott mentions that doping is happening as she speaks:
Rémy Di Grégorio was arresteed during the Tour de France and suspected of doping and of drug trafficking. The London Olympics also had a number of cases.
07:45 A poll among the participants of this conference revealed that 42% said doping can't be stopped, 32% said it's possible in some disciplines, and only 26% thought it can be stopped.
09:30 Max Gassman tells how the biological EPO circulation works (Kidneys -> bone marrow -> erythrocytes -> hematocrit -> oxygen uptake).
15:44 Gassman reveals that the highest Hct measured in humans is 91! They measured Hct of 86-91 in three Peruvian lowlanders who were brought to work in a mine at very high altitude without acclimatization. They were also affected by some cobalt intoxication (in the mines) which further reduced the oxygen intake and therefore caused their system to increase their Hct.
17:55 Gassman shows how transgenetically modified mice with a Hct of 0.80 can only run for a few minutes while wild type mice (typically Hct of 0.40) can run for 75 minutes.
18:55 Gassman mentions Eero Mäntyranta, the Finnish Cross Country skier who had a natural Hct of 0.68.
20:42 Gassman examines the optimun Hct level. For wild type mice, the optimum Hct turned out to be 0.57 (raised from their natural level of c. 0.40 with the use of EPO), while the best Hct for genetically modified mice with a Hct of 0.80 turned out to be 0.68 (Hct was lowered chemically by 'destroying' red blood cells). Graph @ 21:45.
The reason why a higher Hct isn't neccessarily better is because of blood viscosity. The blood becomes too thick.
27:00 Gassmann explains how and why mice with a Hct of 0.8-0.9 don't live very long.
28:48 Gassmann explains Repoxygen (Recombinant epo oxygen gene therapy), and why it was abandoned by its Oxford-based company.
32:00 However, there's a new solution which works on humans! You can take a pill and thereby increase your Hct. "This will be a problem in the future", according to Gassmann, and "not easy to detect".
Here's the summary from the site:
I haven't seen the whole thing yet, only snippets (well, 1 hour I guess). And I doubt there's anything new for the regular clinic posters. But I thought I should share anyway:
http://fora.tv/2012/08/20/Doping_in_Sports_Personal_Cultural_and_Athletic_Impact
It's a pity we're not able to hear the questions from the audience during the presentations. It's also annoying that we don't see what the audience are seeing when the proffessors are pointing at specific parts of their power point charts (we only see the charts as a fixed graphic). The video seems to be downloadable (worked for me).
EDIT:
The original link seems to be down but here is the Youtube link:
https://www.youtube.com/watch?v=aTjpgidjgWE
Overview of the first 35 minutes or so (I will post more headlines later). Times are approximate!
03:46 Kate Scott mentions that doping is happening as she speaks:
Rémy Di Grégorio was arresteed during the Tour de France and suspected of doping and of drug trafficking. The London Olympics also had a number of cases.
07:45 A poll among the participants of this conference revealed that 42% said doping can't be stopped, 32% said it's possible in some disciplines, and only 26% thought it can be stopped.
09:30 Max Gassman tells how the biological EPO circulation works (Kidneys -> bone marrow -> erythrocytes -> hematocrit -> oxygen uptake).
15:44 Gassman reveals that the highest Hct measured in humans is 91! They measured Hct of 86-91 in three Peruvian lowlanders who were brought to work in a mine at very high altitude without acclimatization. They were also affected by some cobalt intoxication (in the mines) which further reduced the oxygen intake and therefore caused their system to increase their Hct.
17:55 Gassman shows how transgenetically modified mice with a Hct of 0.80 can only run for a few minutes while wild type mice (typically Hct of 0.40) can run for 75 minutes.
18:55 Gassman mentions Eero Mäntyranta, the Finnish Cross Country skier who had a natural Hct of 0.68.
20:42 Gassman examines the optimun Hct level. For wild type mice, the optimum Hct turned out to be 0.57 (raised from their natural level of c. 0.40 with the use of EPO), while the best Hct for genetically modified mice with a Hct of 0.80 turned out to be 0.68 (Hct was lowered chemically by 'destroying' red blood cells). Graph @ 21:45.
The reason why a higher Hct isn't neccessarily better is because of blood viscosity. The blood becomes too thick.
27:00 Gassmann explains how and why mice with a Hct of 0.8-0.9 don't live very long.
28:48 Gassmann explains Repoxygen (Recombinant epo oxygen gene therapy), and why it was abandoned by its Oxford-based company.
32:00 However, there's a new solution which works on humans! You can take a pill and thereby increase your Hct. "This will be a problem in the future", according to Gassmann, and "not easy to detect".
Facebook
Twitter
Instagram