This is a tricky one.
As others have pointed out, much depends on how the mutants plan their schedules. Honestly, I don’t see Pogacar or Vingegaard doing the Giro in the next few years at least. However, both will compete in the Tour for many years to come, and I think at least one of them will also ride in the Vuelta regularly (and possibly both).
In this context, riding for UAE might actually be a blessing for Ayuso. On any other team, he’s too talented not to do the Tour, but at UAE, he might be pushed into doing the Giro. The same applies to Almeida, although he seems slightly less talented than Ayuso and more likely to accept a role as a domestique for Pogacar in the Tour.
Since we’re talking about the Giro, which has the weakest lineup of the three Grand Tours, Tiberi and Lipowitz seem the most likely—after Ayuso—to win one. I’ve never been fully convinced of Tiberi’s climbing ability, but he impressed me this year. Lipowitz is more of an unknown, but he seems promising.
I don’t have faith in anyone else in the poll, and in the end, I only voted for Ayuso. There’s also a new generation of riders coming up that will make things even more challenging.