- Mar 4, 2010
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The information below is from a study on the effects of a 500 ml saline infusion on hematocrit and hemoglobin values.
The decrease is pretty small, isn't it? About 3-6% (not percentage points obviously...). Wouldn't you expect more than that from a pint of plasma? The effects remain for a decent amount of time though. Unfortunately they stopped testing after 7 hours, but I'm guessing you could infuse before going to bed and still have a reduced Ht if tested the next morning.
This human albimun stuff that Kohl mentioned and Petacchi may have used is most likely taken together with saline since it maintains oncotic pressure. I suppose it will either make the decrease in crit larger or longer lasting... or both.
http://s3.amazonaws.com/publication...lues after saline infusion and tourniquet.pdfMean hemoglobin concentration (Hb) and hematocrit (Ht) before infusion of 500 ml of saline and every hour thereafter. Ht2 is hematocrit
as measured with the conventional centrifuge method.
Before 1 hr 2 hrs 3 hrs 4 hrs 5 hrs 6 hrs 7 hrs
Hb (g/dl) 15.2± 0.9 14.5±1.0 14.4±0.8 14.6±1.0 14.3±1.1 14.38±1.1 14.6*±1.4 14.6±1.2
Ht (%) 45.6± 2.8 44.0±2.5 43.5±1.8 44.0±2.5 43.4±3.2 42.9±3.3 43.8*± 4.0 43.4±3.6
Ht2 (%) 45.8± 2.7 43.8±2.2 44.0±2.1 44.3±2.5 43.4±3.5 43.3±3.7 43.7±3.6 43.8±2.9
* p < 0.05 compared to pre-infusion value.
Others: p < 0.01 compared to pre-infusion value.
The decrease is pretty small, isn't it? About 3-6% (not percentage points obviously...). Wouldn't you expect more than that from a pint of plasma? The effects remain for a decent amount of time though. Unfortunately they stopped testing after 7 hours, but I'm guessing you could infuse before going to bed and still have a reduced Ht if tested the next morning.
This human albimun stuff that Kohl mentioned and Petacchi may have used is most likely taken together with saline since it maintains oncotic pressure. I suppose it will either make the decrease in crit larger or longer lasting... or both.