Itzulia Basque Country 2025, April 7th-12th

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Duration and level of climber should be an issue. The climb is close enough that it should be a GC battle, if the GC riders start racing against each other, they'll race to keep each other behind, etc.

There's also no immediate descent, which tends to hurt the chances of coming back.
I might have been wrong, because I'm not sure Nys is still in the peloton.