I have biopace and also Rotor rings.
Biopace was on my 20 year old Raleigh. the small 42T ring was biopace with 52T round rings. I don't feel different switching between big and small ring... And as mentioned before, the oval layout is different on the Biopace which is 'big' during the deadzone.
Then on my Cervelo R3 with ultegra 6700 groupset, I tried the Rotor 39T ring with the standard round 53T ring... I can feel the difference going from small (oval) to big (round)... I found that i can maintain >90rpm on the Q ring longer than if I'm using the round rings. Both at approximately same load by playing with the rear gears. So there is a difference going between the oval Q ring and round rings.
Then i come about this Taiwanese brand, Ridea which has their versions of oval rings called Power Rings. I got a good deal and decided to try that instead of the Rotor. It doesn't have adjustable hole but then I can only use the OCP3 big Q ring on the 6700 crank. This Ridea Power rings have a less aggressive +/- 1.5T (less oval)...
Then I bought another set for my other bike, and Ridea 52/36 oval rings with +/- 2T. I'm using this combo primary now....
BTW, the Ridea shifts well on both the 53/39 and 52/36 combos.
I can leave the rear at 28 and shift the front from small to big and the chain ramps up on cue... No loss of shifting smoothness changing out the ultegra chainrings. And Shimano's front shifting is aledi top notch.