Last year, three leaders had about a 30-second advantage over a chasing group of around 20 at the top of the Cipressa.
In the end, these situations depend on the specific circumstances.
Is there a well-defined chase group that can start working immediately? Or are riders scattered into smaller groups, meaning it takes time for an organized chase to form? Whether domestiques and team leaders reach the top together and can start chasing right away, or whether the leaders(domestiques) come over the top first and then have to wait for their domestiques(leaders) to rejoin before the chase can begin.
Many different scenarios are possible. Some favor the chasers, while others favor the leader or leading group. Given that UAE used the Cipressa tactic last year and came close to making it work, and since there does not seem to be any clearly better alternative, I would expect them to try it again.