Yes, too much fruit can cause weight gain. Too much intake of any food can cause weight gain-although some foods are much better to eat in excess than other foods.
Weight gain occurs when a person consumes more calories than he or she expends. Therefore, let's say, hypothetically, that based upon your individual energy needs, you need to consume 2,000 calories to maintain your weight. If, in addition to your regular 2,000 calories, you ate 500 additional calories worth of fruit each day, in one week you would gain one pound. (One pound is roughly equal to 3,500 calories of excess energy stored up in the form of body fat.)
Eating too much of anything will cause weight gain or prevent weight loss. Fruits and vegetables, which are higher in water and fiber and lower in calories than other foods, are less likely to cause weight gain or prevent weight loss, as you would have to eat much larger portions to consume too many calories. However, fruit has almost three times the calories per serving as nonstarchy vegetables, so it is easier to consume too many fruit calories, which can interfere with weight loss. I frequently see patients who think of fruit as a "free food" and are unknowingly consuming up to 250 extra calories a day, which could prevent them from losing one pound of fat every two weeks!
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