I would not underestimate the power of the US congress or the federal government to cause havoc - even if no indictments or actual prosecution takes place. MLB (Major league baseball) long ignored politicians' pleas to clean up itself for the sake of setting a better example for kids dreaming to become MLB stars. The players' union consistently blocked attempts at more punitive anti-doping rules. That was the background for the fall of Barry Bonds, Roger Clemens and many other American baseball heros.
Lance is in a similar situation. He's been clever in the age-old American tradition of appearing to do some good to get cover for his activities which tends to discourage officials and politicians to believe in "rumors", but the public opinion is starting to turn against him. The significance of Landis' statements is that he's targeting the US cycling at large (including possible bribery of the head of an international agency by an American), so the feds have plenty of reasons to investigate.
All it takes now is to get some persistent federal agency official motivated and permitted by his bosses to investigate. Then it does not matter whether there are any federal laws that were possibly broken - the federal investigators know how to use the threat of perjury to get statements to find out what happened.
Those statements will be a matter of public record - or leaked to the press as appropriate. Those who are deemed to have lied, will then be pursued further for lying to federal officials, a serious crime in the US, i.e. no doping laws need to be broken to nail someone.