Yes, but Pantani became an outcast even in Italy, I doubt that Lance already had a big effect on that. Maybe that one had more to do with how it happened, in the middle of a race he was dominating at will and the fact that he was never the same afterwards.
Indurain was not as ruthless as Eddie or even Hinault, he never went for stage wins in the mountains just because he could, usually he was happy to stay with the climbers (who lot minutes in the itts) even when he was stronger. He wasn't the kind of guy who demolished riders on a mountain stage just to prove a point, there are very few instances of him actually going all out on a mountain stage (La Plagne 1995 would be the obvious outliner)