Darryl Webster said:EPO improves performance by 54% in a laboratory trial
This great study, published in the European Journal of Applied Physiology earlier this year, evaluated the effects of EPO use on performance during cycling. We'll try to break the study down as simply and clearly as possible:
Who was tested?
They had 16 reasonably fit cyclists take part in the study. The pre-testing VO2max tests showed an average VO2 of about 3.90L/min and a Peak Power Output of 325 W. By no means world-class cyclists, but fit athletes. This does have some implications for the application of the data, which we'll get to later.
How were they tested?
The testing involved an 13-week period, where the 16 athletes were split into two groups. The control group received placebo injection, whereas the 8 cyclists in the EPO group received a dosage of EPO on a schedule worked out over the 13-week period. One potential problem with the study was that the EPO group could not be blinded that they were receiving EPO, for ethical reasons. What this means is that everyone receiving EPO KNEW that they were, and there's good reason to believe that simply knowing you're receiving a drug improves performance as well! The control subjects were blinded, so they did not know whether they were on EPO or not, which does partly offset this problem.
Measures of performance?
All the athletes were tested BEFORE and AFTER the injections doing two performance-trials:
Peak Power Output testing - here, the subjects start off riding at a low power output and the workload increases every 90seconds until exhaustion. Basically, the cyclist has to go harder and harder until they cannot push anymore! The test is used to measure VO2max and also a Peak Power Output
This was followed by a Trial to Exhaustion at 80% of the previously determined Peak Power Output. In this trial, the cyclist rides at ONE power output - 80% of their maximum, and they ride until exhaustion. This test is used as a measure of endurance performance. This trial was done after 4 weeks and again after 11 weeks of the trial.
The results: A 54% improvement in performance
We don't wish to go into all the blood analysis and DEXA work done - they measured all kinds of things, but this is a post about performance. And the main finding was that EPO use improved time to exhaustion by an enormous 54% within 4 weeks! Peak Power Output improved by 13% in the first four weeks of the trial. The graph below shows the results:http://www.sportsscientists.com/search?q=epo
It think we can be reasonably confident that EPO is worth at least a 10% improvement in performance in elite cyclists. An amount IMPOSSIBLE to for a clean rider to compete with , especially in events were tactics play very little part..time trials.
That is what I have read, from 10 to 20.
