A PubMed search for "cycling and cadence" showed over 150 scientific studies have been published on cadence. The main issues with cadence are economy and efficiency (which usually occur at lower rpms) and muscle fatigue (which is usually less at higher rpms). While there are some contradictory papers, most studies show that performance is decreased and cardiovascular workload is increased at higher cadences. A sample of the results is provided below:
- "higher forces during the low-cadence intervals are potentially beneficial to improve performance" in
Effects of low and high cadence interval training on power output in flat and uphill cycling Eur J Appl Physiol 2011.
- "The energetically optimal cadence decreased after prolonged cycling exercise at a high as well as at a low fixed cadence (P < 0.01). According to the generalized muscle equations of Hill, this indicates that most likely more type I muscle fibres contribute to muscular power output after fatiguing cycling exercise compared to cycling in the beginning of an exercise bout." in
The energetically optimal cadence decreases after prolonged cycling exercise Eur J Appl Physiol 2010.
- "increase in cadence (from 60 rpm to 90 rpm) improves the efficiency of pedalling and the recruitment in both groups (non-cyclists and cyclists)" in
The efficiency of pedalling and the muscular recruitment are improved with increase of the cadence in cyclists and non-cyclists Electromyogr Clin Neurophysiol 2009.
- "Low-cadence interval training (60-70 rpm) is probably more effective than high-cadence training (110-120 rpm) in improving performance of well-trained competitive cyclists. The effects on performance may be related to training-associated effects on testosterone and to effects on maximum oxygen uptake." in
Effects of low- vs. high-cadence interval training on cycling performance in J Strength Cond Res 2009.
- "At a given work rate, very similar efficiency values were obtained at highly different cadences. The discrepancy in the freely chosen pedal rate (FCC)-work rate relationship between the ergometer cycling group and the free cycling group may be related to the manner in which one can regulate work rate. FCC depends not only on work rate but is also affected considerably by the manner in which the work rate can be controlled by cadence." in
Freely chosen pedal rate during free cycling on a roller and ergometer cycling Eur J Appl Physiol 2009
- "Freely chosen pedal rate was found to be approximately 80 rpm at all workloads and was significantly higher than the most economical cadence (50 rpm)." in
Factors associated with the selection of the freely chosen cadence in non-cyclists Eur J Appl Physiol 2009
- "Within the past 10 years, a number of papers have been published that have brought novel insight into the subject. For example, under the influence of spinal central pattern generators, a robust innate voluntary motor rhythm has been suggested as the primary basis for freely chosen cadence in cycling. This might clarify the cadence paradox in which the freely chosen cadence during low-to-moderate submaximal cycling is considerably higher and thereby less economical than the energetically optimal cadence. A number of factors, including age, power output, and road gradient, have been shown to affect the choice of cadence to some extent. During high-intensity cycling, close to the maximal aerobic power output, cyclists choose an energetically economical cadence that is also favorable for performance. In contrast, the choice of a relatively high cadence during cycling at low-to-moderate intensity is uneconomical and could compromise performance during prolonged cycling." in
Factors affecting cadence choice during suboptimal cycling and cadence influence performance Int J Sports Physiol Perform 2009
- "During cycle bouts of short duration (<15 min), it has been well argued that experienced cyclists, trained runners and triathletes adopt high cadences (80-100 rpm) systematically above the energetically optimal cadence (EOC) at which the oxygen uptake is minimal (55-65 rpm). The choice of a high cadence has been shown to be dependent upon several factors, such as the aerobic fitness level, the reduction in forces applied to the cranks, the lower extremity net joint moments and minimal neuromuscular fatigue. However, with increasing exercise duration the FCC has been reported to be close to the EOC exclusively in endurance athletes practising a variety of activities ..." in
Which factors determine the freely chosen cadence during submaximal cycling J Sci Med Sport 2010
- "Lower cadences were more effective during the recovery phase for both intensities and freely chosen pedal rate was the best technique during the propulsive phase." in
Cadence and workload effects on pedaling technique of well-trained cyclists Int J Sports Med 2008
- "Cardiac output (CO) was higher at 100 rpm ... VO2 at both workloads was greater at 100 than 80 rpm as was HR. Results suggest that increases in O2 demand during low submaximal cycling (50 % VO2max) at high cadences are met by HR-induced increases in CO. At higher workloads (65 % VO2max), inability of higher cadences to increase CO and O2 delivery is offset by greater O2 extraction." in
Cardiovascular effects of cadence and workload Int J Sports Med 2008
- "A high pedaling cadence (i.e., 120 rpm) reduces performance (i.e., W(max)) and anaerobic threshold during an incremental test in well-trained cyclists." in Med Sci Sports Exerc 2006
Here are some general articles on cadence from the web:
http://www.mybetterhealthforums.com/optimal-pedaling-cadence-what-is-best-and-why/index.html
http://jon-sparks.suite101.com/cadence-for-better-pedalling-a12791
http://www.slowtwitch.com/mainheadings/coachcorn/cadence.html
http://beginnertriathlete.com/cms/article-detail.asp?articleid=433