FrankDay said:
Phooey. Well, I guess it could be a mechanism if it actually explained the data but there is zero quantitative data to support this speculation, especially to explain the drop in CO as one exercises beyond VO2max. Your explanation should result in a leveling of CO at VO2max but cannot explain the drop.
Phooey yourself. Not only does it explain both the leveling and the drop, but as I just showed you there are data to support this conclusion.
FrankDay said:
But, the heart behaves the same at VO2peak as it does at VO2max
No, it does not. As an example, even most lay individuals involved in endurance sports are aware that you cant achieve the same heart rate when cycling as when running (unless, of course, you are a trained cyclist).
FrankDay said:
, with CO dropping.This is a BS argument because the only way we know that something isn't VO2max is because later we come along and test another way and get a higher number. One can never be certain that any given test actually tests an athletes VO2max.
The fact that the integrative physiology of exercising humans is difficult to safely dissect in no way means that the conclusions of such research isn't true.
FrankDay said:
You don't seem to understand that I agree that it appears that the heart (or the CV system, if you insist) is the limiter to athletic performance (or VO2max) if one has an incomplete understanding of the underlying physiology. However, such a simplistic view of the data doesn't address the mechanism to explain this limitation.
Yes, it does: with ever-increasing sympathetic stimulation, the heart is pushed beyond it's optimal frequency of contraction (a simplistic analogy is the way that an internal combustion engine reaches maximum horsepower at an rpm less than maxium).
FrankDay said:
How, exactly, can we explain the way CO drops off after VO2max is reached (or, even before it is reached if we look at VO2peak or even lesser workloads continued for longer periods)?
I already told you: the heart keeps beating faster and faster, but with less blood pumped with each beat, so that cardiac output and, hence, convective O2 delivery, actually fall, leading to a plateau (and sometimes even a "peaking over") in whole-body VO2.
FrankDay said:
Are there any other things going on at the same time that might explain this phenomenon?
LOTS of things are going on under such an extreme emergency situation for the body. The fact remains, however, that VO2max is not limited by, e.g., some "central governor" as wrongly believed by Noakes or by peripheral O2 utiliation, but the cardiovascular system's ability to deliver said O2.
FrankDay said:
How does one explain the heart seemingly adapting to training such that it is possible for the sedentary to increase VO2max with training or the drop in VO2max as one stops training? What specific change (or changes) in the heart explains these changes that are seen?
I know it's hard for you, Frank, but I think (or at least hope) you'll be less confused if you first focus on understanding the responses to acute exercise, rather than worrying about chronic adaptations.
FrankDay said:
Rather than snickering at the knowledge of your average (cardiac) anesthesiologist
Don't worry, Frank, I'm not - I only snicker at you.
FrankDay said:
How can we explain stroke volume going up in athletes for the same filling pressure despite, sometimes, thickened myocardium which should, one would think, reduce stroke volume?
What did I just tell you about not confusing the acute responses and chronic adaptations to training?
Anyway, it is well-established that endurance training increases ventricular compliance (and that the increase in wall thickness in endurance-trained individuals is merely proportional to the increased EDV...Laplace's Law and all that).
FrankDay said:
Perhaps you might learn something about underlying cardiac physiology by looking at how the CV system responds and is limited in other conditions associated with high oxygen consumption from muscle activation, such as malignant hyperthermia, or conditions that affect the hearts ability to respond to stress in the operating room and how to treat them.
Malignant hyperthermia is not exercise (though they have similarities).