My thoughts
I think Contador and Schleck should dominate the real tour, and if true you'll need one of the two to win this. Not sure both are possible on one team while still maintaining enough points with the other riders. They were by far the two most valuable riders last year in this game (with Schleck actually earning more points). I like Schleck as a better value for a few reasons.
I'd agree that the second GC rider requirement is a burden. Not sure any of the 10-14 point guys earn many points, although I'm intrgued a bit by Kloden, Vino, Hesjedal, and Martin. One of these guys probably does decently well. Martin not so much overall, but if HTC wins the TTT, then he may be able to rack up some early points for being near the top of the leaderboard.
Same problem with the Climbers. You need two, but not sure anyone worth 10 or less earns much. Mouncoutie's midly interesting. But I'd rather spend at least 12 on someone who might earn something than 6-10 on someone likely to get minimal points. Also weird that many GC candidates lurk here. After AC and AS, the next 4 overall finishers could come from this group (Samu, VDB2, Gesink, Schleck the Elder).
Sprinters - would love Cavendish, but not sure how to fit him in money wise.
Domestiques - Having Horner here is interesting. He's probably equal to Leipheimer at half the cost, but not sure either earns that many points. Budgeting getting tough.
Wild-card - I tend to like a second sprinter here