You can certainly take the position that it doesn't change much, but I don't think you have much to stand on. Andy was always in a no-win situation. If he beats Contador this year, it's not because he was better, but because Contador already won a GT this year. If he loses to Contador, well, it just underscores his weakness. That was BEFORE the bullsh*t crash on Stage 1 and the spate of crashes. Now he's got a possibly Giro-depleted Contador who has a serious knee injury. Now he has a much worse lose-lose situation IMO.
As for Cuddles, this is obviously less of an issue for him since he had two rather crappy TdFs the last couple of years. So maybe I overstated the initial case for him.