Coronavirus: How dangerous a threat?

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I myself am advocating for Julian Assange to be prosecuted, and punished to the full extent of the United States law. If Wleekers played any part of an cyber intrusions of Covid data at any level,or tried to track vaccine data in any way,that would be very serious. Mr.Assange has been confirmed as a source of US troop data, of various kinds including classified positioning data,and names,home address, social security numbers and other data of US military members.
Any party found to have hacked anything to do with Covid 19 should be tried under wartime,enemy combatant directives.
I also find the publication of Border Patrol agents personal data deplorable, I hope that a justice system, US or other can try Julian for the crimes he is accused of,as well as the crimes he has publicly admitted.
current administration has not pursued almost anything cyber serious, serious security defects and bad actors could interrupt the supply chain with what looks like the greatest of ease..
You will probably get you your wish as the Australian government doesn't seem too interested and the British governemt will probably honour it's legal agreements with the USA especially while Boris Johnson is in power. I guess there are only so many avenues of appeal. Probably an issue that Biden would rather sidestep as well. Assange might have some hope on health grounds but its unlikely.
 
This is the kind of story that reinforces the belief that when it comes to avoiding contact with others, you can never be too paranoid. A woman spent forty minutes, sitting by an open window, at her son's apartment, while her daughter gave the son (the daughter's brother) a haircut. The daughter worked at a salon, which is fairly risky, but she had tested negative several days earlier, and had quarantined following that test. They all wore masks.

The daughter developed symptoms the next day--which means she would have been maximally infectious when with her mother and brother. The mother and brother developed symptoms soon after, followed by the mother's husband, who hadn't been present at the haircut. The mother and her husband both died, ten days apart.

 

Chris Gadsden

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Can’t win for losing.

From a global production projection of 52 billion masks for 2020, we estimate that 1.56 billion masks will enter our oceans in 2020, amounting to between 4,680 and 6,240 metric tonnes of plastic pollution. These masks will take as long as 450 years to break down and all the while serve as a source of micro plastic and negatively impact marine wildlife and ecosystems.

https://oceansasia.org/wp-content/uploads/2020/12/Marine-Plastic-Pollution-FINAL-1.pdf
 
I read there is half milion people vaccinated in Israel already. I read in slovak newspaper so I dont now if it is true. How they could have so many vaccines availaible? With this pace I expect in february they have to suppress virus greatly and deaths at the minimum with march april with normality. I am curious. Israel is now guinea pig.

I don't have the source at hand right now, but yesterday I read that Israel pays $30 per dose to Pfizer, compared to $18 the EU has negotiated. That may help to speed things up quite a bit of course
 
Bahrain and Israel are leading the way with vaccinations at this point. Israel think they can have all their vulnerable vaccinated twice by the end of next month. They are also doing another lockdown to minimize the mortality in the meantime. They are considering 24-7 centers to speed it up to a target of 150k a day. That would be like 4 million a day in the USA.
I don't understand how Israel could get so many vaccines so fast. The problem here is not that the logistics, but the lack of vaccine. Would it really be that if you pay more, you get them faster (see above?). That would be scandalous.

In other news, the UK greenlighted the Oxford-Astrazeneca vaccine, while the EU medicine bureau has said they haven't received all the required documents from them, and they haven't even formally applied for regulatory approvement. So what's the game here?
 
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I guess it's mainly the UK being a bit desperate atm, otherwise rushing to get a less effective vaccine out makes little sense.
To my understanding the EU didn't want to put all of their eggs in one basket early on, so they made deals with multiple companies to get their vaccines and not just one.
Speaking of vaccines, are there any legit studies about Sputnik V (the Rusdian one)?
 
Heads up, Nomad, the variant is in your neck of the woods. Not terribly surprising news, but noteworthy.
And a second case of the variant was just found yesterday involving some workers at an assisted care facility located in a small town outside of Colorado Springs:


And just when the situation here is looking very good with cases plummeting to levels not seen since early fall. And hospitalizations were also trending downward until a few days after Christmas where we're seeing a slight uptick.

If two cases of this new variant is found here in some rural areas of Colorado, certainly the variant must be all over the U.S. and it's matter of time before positive cases will be detected?

I also see where the vax manufacturers say they "believe" the vaccines should be effective for this variant. Just how certain are they if they use the word "believe" where maybe in reality the vaccines will not be that efficacious?

And can you imagine the panic in this country if the vaccines are determined to not be effective against this variant. If people think things were bad last spring, they haven't seen nothing yet. Since so many Americans are terrified of COVID-19 and live a life in constant fear and panic, not having a vaccine to save the day would be devastating to these people.
 
I don't understand how Israel could get so many vaccines so fast. The problem here is not that the logistics, but the lack of vaccine. Would it really be that if you pay more, you get them faster (see above?). That would be scandalous.

In other news, the UK greenlighted the Oxford-Astrazeneca vaccine, while the EU medicine bureau has said they haven't received all the required documents from them, and they haven't even formally applied for regulatory approvement. So what's the game here?
I don't know anything about that end of the process, but I wouldn't rule it out. Could explain why Bahrain is also doing so well. Here is an example of how those two are lapping the field when it comes to vaccination.
View: https://twitter.com/thehowie/status/1344273969889779712

I guess it's mainly the UK being a bit desperate atm, otherwise rushing to get a less effective vaccine out makes little sense.
To my understanding the EU didn't want to put all of their eggs in one basket early on, so they made deals with multiple companies to get their vaccines and not just one.
Speaking of vaccines, are there any legit studies about Sputnik V (the Rusdian one)?
The AZ vaccine did seem to do comparably well as the mRNA vaccines at limiting severe disease, although the studies were not really designed to examine that precisely. Anything over 50% efficacy is going to be approved IMO as long as the safety data is tolerable.

The Russian vaccine makers published the early trial results, but AFAIK the efficacy numbers from the Phase III were reported but not published. It did seem to do well with the two important parameters. It induced antibody and generated T cell responses. In theory, the heterologous prime boost strategy they are using would be expected to work better than the AZ vaccine which uses the same adenovirus formulation as the prime and the boost. Using a live virus in the vaccine, there is always going to be an extra scrutiny on safety. Would be curious to know what they found after vaccinating thousands with it.
All participants produced antibodies to SARS-CoV-2 glycoprotein. At day 42, receptor binding domain-specific IgG titres were 14 703 with the frozen formulation and 11 143 with the lyophilised formulation, and neutralising antibodies were 49·25 with the frozen formulation and 45·95 with the lyophilised formulation, with a seroconversion rate of 100%. Cell-mediated responses were detected in all participants at day 28, with median cell proliferation of 2·5% CD4+ and 1·3% CD8+ with the frozen formulation, and a median cell proliferation of 1·3% CD4+ and 1·1% CD8+ with the lyophilised formulation.

If two cases of this new variant is found here in some rural areas of Colorado, certainly the variant must be all over the U.S. and it's matter of time before positive cases will be detected?

I also see where the vax manufacturers say they "believe" the vaccines should be effective for this variant. Just how certain are they if they use the word "believe" where maybe in reality the vaccines will not be that efficacious?

And can you imagine the panic in this country if the vaccines are determined to not be effective against this variant. If people think things were bad last spring, they haven't seen nothing yet. Since so many Americans are terrified of COVID-19 and live a life in constant fear and panic, not having a vaccine to save the day would be devastating to these people.
Yes, I would think so. The person yesterday was not someone who had been to the UK, so that almost assuredly means there is some community spread. But I doubt that it is super widespread as sequencing these viruses is pretty common and it has not been seen elsewhere and I know that they were looking in CA based on how bad certain areas were getting. It is bad in areas there, but not because the variant. NY and the tristate area probably have it based on flight connections to Europe. Where it is seeded beyond that can be somewhat coincidental. We saw that in the spring where Detroit got hit hard along with NYC, but other major cities were not as immediately effected.

For better or worse, that is how scientists talk. If they are not certain, they don't want to say that they are. Based on the structural analysis of the mutant Spike variant, there should be protection with the vaccine. Data from the UK indicate that, but it is not a sure thing at this stage though. An escape mutant would be one of those worst case scenarios that I've alluded to before that would really derail the recovery. No question about it.
 
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Of course it doesn't. In the first place, at that time, the virus hadn't been sequenced, so no one knew that it wasn't SARS. I repeat: at the time Li was forced to recant, there was no way of knowing whether the virus was the original SARS. So there was no proof that his information was false, at the time that he was forced to recant it.

In the second place, when Li mentioned SARS, he was quoting the report of another doctor, who treated these patients. And he specifically added that the exact type of SARS had not yet been identified. So there was nothing in his posting that was false. He was forced to take back his statement of seven SARS cases, when that statement was factually true.

The "slap on the wrist" was in fact a threat of prosecution if he communicated to others anything about the virus and the disease.

The virus sequence not being sequenced yet is the exact reason why he shouldn't have spread rumors about it being SARS. The exact type of SARS? LOL! At that stage there was only 1 type of SARS (the one from 2003), the virus wasn't even called SARS-COV-2 at that stage prior to the virus being sequenced, the only thing similar to SARS was the disease symptoms, so saying it was SARS was 100% false information. He should have called it a new unknown respiratory illness or similar, instead of jumping to incorrect conclusions, like here: https://www.nbcwashington.com/news/...zens-at-virginia-retirement-community/135890/


What false information? You still haven't provided any.
Four years in jail for knocking over a barrier or something? Seriously?

Zhang Zhan is not a journalist, she had no journalistic credentials. Therefore she's not free press. Journalism requires facts by definition; you can't do journalism with lies. That's called a propagandist. Adding a ridiculous epithet ("citizen journalist") to the term doesn't free you from real world consequences of false reporting. To top it off, she's a lawyer and rant is typical of a petit-bourgeois/middle class ideologue: freedom of the individual above the collective good; moral values above social values. Finally, as I laid out above, she is on the payroll of the US under the CHRD organization, aka a CIA asset, https://www.nchrd.org/2020/09/zhang-zhan/ so she has an agenda for her rioting.

Not provided false information? LOL! Did you even look at her videos and interviews before trying to defend her actions? How about his: Our brave and free Ms. Zhang records herself harassing a medical checkpoint in Wuhan
View: https://www.youtube.com/watch?v=7K4SBNhYoQs&feature=emb_title

How about this interview with U.S. government financed Radio Free Asia , when Wuhan had already defeated the coronavirus but faced with a few new infections in May, resulting in the government testing all 11 million people in Wuhan: https://www.rfa.org/english/news/china/residential-05142020110658.html
"There are police outside on the street now guarding the place, and no vehicles are being allowed through," Zhang said. "I asked a nearby resident how many people were taken away in ambulances, and he told me that 180 people were taken away for isolation."
"The barriers have been put back and the place is under lockdown," Zhang said. "There is also an online announcement saying that delivery drivers aren't being allowed to enter certain compounds."
"There are signs of a resurgence of the epidemic in Wuhan."

There was no resurgence of Covid-19 in Wuhan. No new lockdown. Just 6 confirmed cases, and the rest asymptomatic cases found during the city-wide testing, which was soon resolved. Biased and false information hoping to cause panic. Check.

I can't believe your ignorance of the U.S. It is absolutely jaw-dropping. Hello, protests like this happen ALL THE GD TIME in the U.S. People have gathered in front of governors's houses to protest the pandemic measures. They have held anti-lockdown rallies. Individuals have caused disturbances in stores by not wearing a mask (they are told to leave the store, but they aren't arrested). They have protested outside hospitals, claiming that the C19 cases aren't real. No one gets arrested for this stuff, unless there is actual violence.

Was the US ever in strict lockdown forbidding entry/exit like Wuhan was in late January? Zhang Zhan broke into quarantine in February, defied lock-down orders for which she should have been punished. She was in China, not the US, and violated the country's laws, confidentiality rules, quarantine rules, etc. and that's even if we don't consider her likelihood acting as a CIA foreign agent, hence these are criminal acts and deserves punishment. China was faced with what the west called its "Chernobyl Moment", and millions of people would have had their lives ruined if no action was taken, and this Zhang woman did the best she could to actually make that tragedy happen, by trying to persuade the populace that they should turn against the Chinese government in the middle of a serious national crisis, and ignore the quarantine rules the government had set to keep people alive. And you still want to defend this wacko and that she doesn't deserve punishment for what she tried to do?

An increase of 12 times from the previous year. IOW, this is an extraordinarily different year, very different from what usually is the case. Why? Because of the BLM protests. Protests such as these would never even be allowed in China.

When journalists covered the protests, it was hard to distinguish them from people who might have been breaking the law. Most of these journalists were "detained", i.e., stopped and questioned. Very few, if any, were jailed, and none was jailed for any length of time remotely approaching four days, let alone four years. And of course there was outrage over it. Again, get a grip.
Where is the outrage? Where are the simultaneous outpouring of support from all MSM outlets regarding each of the arrested journalists? Where are the lists naming each of these 100+ arrested journalists? There are none, because these people only gain a name and unbridled western media support when they are arrested in China, at the same time ignoring all their misbehaviors, history of causing troubles, and the real reasons behind their arrests.

Again, you're going around in circles, contradicting yourself. See the picture in that link you posted? See all the people protesting in support of Assange? Think that would happen in China? Do you think any media in China would be allowed to post an article critical of the government like that? Do you think there are public forums like this one in China, where people constantly, day in, day out, criticize the government?

I myself am not advocating that Assange be prosecuted. But the documents he published have put many people at potential risk. Again, trying to compare this to what Li did is a total joke. Only someone who is blinded by China-love, who absolutely, positively to save himself cannot utter one single word critical of China--unlike I and most other posters on this thread, who constantly, day after day after day, criticize the U.S. government. The amount of anti-U.S. government criticism posted on this thread is at least fifty times the amount of criticism of China, but you can't handle any criticism of China whatsoever.
I accept all legitimate criticism of China, but posting MSM propaganda pieces defaming China based on lies is laughable. Earlier, I posted that in mid January, the authorities should definitely have acted quicker, and caused a week's delay in confirming new positive cases by requiring both PCR and chest scan positives. Almost every single one of my posts have been debunking outright lies (virus created in a lab; 20+ million people died in the first 2 months based on cellphone and crematorium data; outbreak began much earlier based on false parking lot satellite data and web search results; "disappeared" journalists, etc. ). Notice a trend? Only someone who has seen nothing but MSM propaganda their entire life would believe anything coming out of the corporate media regarding criticisms on China, regardless of accuracy, without knowing the whole story.
 
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I don't understand how Israel could get so many vaccines so fast. The problem here is not that the logistics, but the lack of vaccine. Would it really be that if you pay more, you get them faster (see above?). That would be scandalous.

In other news, the UK greenlighted the Oxford-Astrazeneca vaccine, while the EU medicine bureau has said they haven't received all the required documents from them, and they haven't even formally applied for regulatory approvement. So what's the game here?


I read somewhere (if I can find it again I'll post the link) that the way the UK approved the AZ vaccine is to get the two full doses 3 months apart and they think that should be 80% effective.
 
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I now came across a similar number on CNN, but it still seems like a bit of a guess:

Updated advice
Previously, the team developing the Oxford/AstraZeneca vaccine said it had an "an average efficacy of 70%," with one dosing regimen showing an efficacy of 90%.
But the experts who gave Wednesday's Downing Street briefing said a full analysis of the trial data had not borne out the team's finding that that regimen -- in which a half dose was followed by a full dose -- was more effective. The MHRA approved the vaccine at two full doses, which has an efficacy of 62%.
Prof. Munir Pirmohamed, chair of the Commission on Human Medicines' Expert Working Group, said the trial data had led scientists to recommend giving as many people as possible their first dose of vaccine with a second dose following within 12 weeks.
"Because of the design of the trial, some people got second doses at different time intervals. This allowed for an analysis of the effectiveness of the vaccine if you were to be able to delay between 4-12 weeks," he said. "This showed that the effectiveness was high, up to 80% when there was a three month interval between first and second doses, which is the reason for our recommendation."
Pirmohamed noted that partial immunity only kicked in 22 days after the first dose and urged people to continue to follow social distancing guidelines even once they have had their first jab.
UK government scientific adviser Professor Calum Semple welcomed what he called a new, "sophisticated approach," telling Sky News that a "one-dose approach to start with will protect a great many people." According to Semple, evidence from vaccine trials has shown that a single dose has not only prevented people from getting severe disease, but also has prompted a "very good immune response" in frail and elderly people.

However, some scientists called for greater clarity over the data underpinning the latest vaccine approval and the country's new immunization strategy.
Dr. Jonathan Stoye, of the Francis Crick Institute, told the UK's Science Media Centre that important questions remained unanswered, including the real efficacy of the vaccine, how well it worked in older people and whether it prevented transmission between people.
"It remains unclear exactly how much protection is offered, and the regulators are using unpublished data to come to their judgment," said Dr. Simon Clarke, Associate Professor in Cellular Microbiology at the University of Reading.
"When questioned, the regulators floated an efficacy of 70% between 22 days and 12 weeks, but it seems likely that this is a fleeting maximum rather than a consistent level of protection. The vaccine's efficacy after two doses is 62%, so it looks likely that the higher number would only be very short-lived.
"At a time of increasing rates of infection, hospitalization and death from Covid-19, greater clarity is urgently needed over any risks associated with extending the second dose window to 12 weeks."
 
Looking at their data, the antibody titer was about 3 fold greater in the group that waited more than 12 weeks than those who got it on schedule. You can see an increase in the group with a vaccine interval of 9-11 weeks compared to <6 weeks too, so the data is internally consistent. Based on what they submitted, this strategy wasn't really intentional, just how the second dosing went due to 'logistical constraints'. About 60% of the vaccine group got it in <6 weeks with about a quarter of that number in the other groups. The control was not even consistent in the study as some got saline while others got the meningococcal vaccine. That design is not how you draw it up on the chalkboard, but they seem to have learned something useful by being imprecise. Really a bit of a mess that only survives because we are deep in the ####.

It isn't clear to me where the efficacy number came about either.
 
Looking at their data, the antibody titer was about 3 fold greater in the group that waited more than 12 weeks than those who got it on schedule. You can see an increase in the group with a vaccine interval of 9-11 weeks compared to <6 weeks too, so the data is internally consistent. Based on what they submitted, this strategy wasn't really intentional, just how the second dosing went due to 'logistical constraints'. About 60% of the vaccine group got it in <6 weeks with about a quarter of that number in the other groups. The control was not even consistent in the study as some got saline while others got the meningococcal vaccine. That design is not how you draw it up on the chalkboard, but they seem to have learned something useful by being imprecise. Really a bit of a mess that only survives because we are deep in the ####.

It isn't clear to me where the efficacy number came about either.

The more I see about the AZ vaccine the more I'm convinced they need to completely redo their phase 3 trial.
 
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Slaoui agrees with you. He estimates that they are going to have to wait until April to see how more of the US trial is progressing before applying for the EUA. Better news from him is that the single dose J&J vaccine is about to unlock their results very soon.
 
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I do hope the J&J vaccine's numbers will be good. That would be a game changer. Seeing the Sinopharm vaccine is reported to be 79% effective, I would expect companies with more experience in vaccine design to have at least this kind of efficacy. It remains to be seen whether J&J could do it with 1 dose, as they were also testing a two-dose-regimen unless I'm mistaking.
 
I do hope the J&J vaccine's numbers will be good. That would be a game changer. Seeing the Sinopharm vaccine is reported to be 79% effective, I would expect companies with more experience in vaccine design to have at least this kind of efficacy. It remains to be seen whether J&J could do it with 1 dose, as they were also testing a two-dose-regimen unless I'm mistaking.

I agree that it's going to be interesting to see what the J&J numbers look like. I don't remember if they were doing a two-dose trial as well as the single dose. If their single dose produces high numbers, I agree that it would be huge.
 
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An arshat on fox said that people who get killed by sharks get put on the Covid death list if they test positive.
-Why would they do a Covid test on someone who was killed by a shark?
-How many people died of shark attacks this year (8 )? Was it enough to inflate the Covid numbers (no)?

Its bad enough that this idiot would say this, but even worse, ignorant people eat this crap up and repeat it over and over.

*Disclaimer: I was watching "American Restorations" on fox while doing some work, it ended, and the mid-day 'news' came on.
 
Look at how many are saying the 41 year old LA House member died from a heart attack. Just happened to be in the ICU with COVID at the time. Purely coincidental, I'm sure.

J&J are doing two trials. The two dose trial is using ~2 month interval. I don't know when that one is predicted to be finished. Probably in time to know whether the people who get it first should get it again later for more protection.
 
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Look at how many are saying the 41 year old LA House member died from a heart attack. Just happened to be in the ICU with COVID at the time. Purely coincidental, I'm sure.

J&J are doing two trials. The two dose trial is using ~2 month interval. I don't know when that one is predicted to be finished. Probably in time to know whether the people who get it first should get it again later for more protection.

Thanks. They should start reporting data for the 1 dose trial sometime in January.
 
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On Tuesday the US recorded the highest death toll of pandemic. 3628 people lost their life to the virus. I guess this is the result of so many people being complacent of risks at Thanksgiving?

Very very sad. But worse I read today that air travel still increased across the US despite the overwhelming facts. That means ever more deaths on the way. :(

Question: Is American love of freedom the root cause of US carnage?

Record COVID-19 hospitalisations in US could soon force health experts to ration care

The US also reported more than 124,600 COVID-19 patients nationwide, the highest number the country has seen, putting a major strain on hospitals.
In Los Angeles County, people hospitalized for the virus are at an all-time high and nearing 7200. This number is up almost 1000 per cent from two months ago.
In Los Angeles, at least five hospitals have been forced to turn patients away due to oxygen supply issues, state officials say.
 
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Chris Gadsden

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Question: Is American love of freedom the root cause of US carnage?

Certainly a contributor.

I think the problem isn’t only the love of liberty... I don’t think we have “leaders” capable of persuasion And it does not help given how already polarized we are and it does not help when the public knows they are constantly lied to by corporate media. Which “truth” is to be believed?

You’ll get very little compliance from Americans by ordering them to do something even if it’s for their own good. Asking them, begging them and showing them ‘why’ with real data, not made up BS will help a lot.

I guess we will have to save that for next time.
 
On Tuesday the US recorded the highest death toll of pandemic. 3628 people lost their life to the virus. I guess this is the result of so many people being complacent of risks at Thanksgiving?

Very very sad. But worse I read today that air travel still increased across the US despite the overwhelming facts. That means ever more deaths on the way. :(

Question: Is American love of freedom the root cause of US carnage?

Record COVID-19 hospitalisations in US could soon force health experts to ration care
The short answer is yes. The long answer is too long and would end up wit ha lot of OT for here.