Doping kills people early on

East Germany was really one of the worst doping regimes to be in. Like throwing every damn hormone on you they thought of as performance enhancing, making athletes to guinea pigs. Also a lot of pain killers to deal with absurd volumes and a lot of pressure and bad treatment. Sample also includes a lot of strength-focused sports where the high weight alone puts a lot of strain on the cardiovascular system.

TdF cyclists, while also associated heavily with doping, tend to live longer than their average non-athlete peers, for example.

So I would say it depends. On the substance, on the dosage, on what you want to achieve with it, ...
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