General Doping Thread.

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Re:

Cake said:
In 5/10 years time, when hundreds of retired former sports pros are suffering from health issues despite being in the physical group least likely to suffer from them, the truth will not be deniable anymore.
Given we've had doping since the c19th, given we've had serious doping since post WWII, how has this worked out with past generations, particularly in cycling?
 
Jun 30, 2014
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snccdcno said:
Saw someone asking why Diniz wasn't at Funvic this year in PRR section during Catalunya and this came out today so thought I'd post it!

http://www.uci.ch/pressreleases/uci-statement-alex-correia-diniz-otavio-bulgarelli-and-the-uci-professional-continental-team-soul-brasil-pro-cycling/
Thanks, at least in his chase it's passport related and not just testing positive for CERA like the other guys, but that makes sense,the guy was decent at races that have at least some decent testing like Utah and San Luis, he wass probably smart enough not to dope durning those races and was only caught by the passport.
You could probably come to a similar conclusion when it comes to Dani Diaz, h only peaked for San Luis and was never a factor in the South American races that are known for having pretty low testing standarts/riders going full ***, yet he hasn't been the same since he moved to a PCT team that is a part of the passport program.
The testing at PCT level really ruined Funvic, they should have stayed at CT level where you are alowed to go full *** in certain races and not have to worry about the passport.
 
Re: Re:

Mayomaniac said:
snccdcno said:
Saw someone asking why Diniz wasn't at Funvic this year in PRR section during Catalunya and this came out today so thought I'd post it!

http://www.uci.ch/pressreleases/uci-statement-alex-correia-diniz-otavio-bulgarelli-and-the-uci-professional-continental-team-soul-brasil-pro-cycling/
Thanks, at least in his chase it's passport related and not just testing positive for CERA like the other guys, but that makes sense,the guy was decent at races that have at least some decent testing like Utah and San Luis, he wass probably smart enough not to dope durning those races and was only caught by the passport.
You could probably come to a similar conclusion when it comes to Dani Diaz, h only peaked for San Luis and was never a factor in the South American races that are known for having pretty low testing standarts/riders going full ***, yet he hasn't been the same since he moved to a PCT team that is a part of the passport program.
The testing at PCT level really ruined Funvic, they should have stayed at CT level where you are alowed to go full *** in certain races and not have to worry about the passport.

Watch W52 make the same mistake next year
 
Funvic Soul Brasil team facing second doping suspension -
http://www.cyclingnews.com/news/funvic-soul-brasil-team-facing-second-doping-suspension/
The UCI announced the Adverse Passport Finding against Alex Correia Diniz and his provisional suspension. The governing body also announced that "Autoridade Brasileira de Controle de Dopagem asserted an Anti-Doping Rule Violation for Tampering against the Brazilian rider Otavio Bulgarelli". Neither Diniz or Bulgarelli are contracted riders for the team in 2017 but raced with the team in 2016.

Diniz previously tested positive for EPO in 2009 and received a two-year ban from the sport. The 31-year-old signed with the Brazilian team in 2013 and made and instant impact by winning the queen stage of the Tour de San Luis and finishing third overall. His last race was the 2016 Tour of Taihu Lake where he placed 15th overall. Bulgarelli, 32, was the 2012 Brazilian national champion and last rode at the 2016 Volta a Portugal where he failed to finish stage 3.

The Funvic Soul Brasil team was suspended for 55 days for three doping cases in a 12-month period and was only allowed to start their 2017 season on February 12.

As a consequence of further multiple anti-doping violations, the team risks a suspension between 15 days to 12 months, dependent on the Disciplinary Commission which the UCI said will make its decision in "due course."
 
Apr 3, 2016
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Having trouble embedding the image above, says its too big and im not sure how to resize. Im writing a literature review on a technique called hot embossing and came across a paper on micro needles. In the paper it says

"Dissolving microneedles have been used to deliver EPO(...) and human growth hormone."

A dissolving microneedle is like a patch you put on your skin, the needle just pierces your skin leaving the needles to disolve and the drugs to be administered into your body. This would leave almost no mark on the skin from administering, does not need any medical professional to administer, and i suspect would only administer a very small amount of the drugs at a time.

Perfect way to microdose and no risk of leaving behind empty vials/ syringes?

Original paper- "microneedles for drug and vaccine delivery" (2011)
EPO- "Self-dissolving micro-pile array chip as percutaneous delivery system of protein drug" (2010)
EPO-"Self-dissolving micro-needles for the percutaneous absorption of EPO in mice" (2006)
HGH-"Two-layered dissolving microneedles for percutaneous delivery of peptide/protein drugs in rats" (2011)
HGH-"elf-dissolving micropiles for the percutaneous absorption of recombinant human growth hormone in rats" (2008)
HGH-"Dissolving microneedle patch for transdermal delivery of human growth hormone" (2011)

Sources just there if anyone has time to sift through for some more information, not seen it mentioned before on here. I'll be reading through them in the future however I don't have the time to sift through papers at the moment.
 
Apr 3, 2016
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Re:

Netserk said:
Is it then injected intravenously?


I'll have to read more on the subject when I get time. I was hoping some one with a more medical background would be able to explain how well this would work. Further on in the paper it says how insulin can be administered in this method and adjust blood sugar levels.

My degree is in mechanical engineering, I was only reading about this because of how they are made. When I saw EPO and HGH mentioned I thought it was interesting, I'd never read about microneedles on here and was basically hoping for further explanation by a more medically minded person.

Edit: From what I gather, they aren't as effective as injecting with a hypodermic needle, but far more effective than taking anything orally or directly onto the skin. they are "large enough to deliver almost any drug or small particle formulation"

Thanks for editing Irondan.
 
Is blood doping probably still the status quo? Or micro dosing EPO instead?
For blood doping... how much recovery time after withdrawing blood is needed to build up a good blood supply for the season? Can the blood be stored for many months?
 
^ I don't think its either or but both and when it comes to (microdose) epo and blood transfusions. The transfusion cycle basically requires epo to be effective under a heavy training load.

Refrigerated red cells endure ca four weeks. After that they need to be reinfused. Frozen they can last longer, but some loss of rbcs is expected using this method. It is also more expensive.

As a separate observation..... Watched several editions of amstel and fleche during the week on YouTube from 1999 on. It is quite astonishing how markedly the anthropometry of the riders and the top contenders in particular changes over the years. To wit, they become a lot thinner. This is not something new of course, but the change becomes very pronounced when the footage from 20 or so years is compressed like so. One illustrative example would be the disappearance of riders with body types like bettini from the finales of hilly classics. Another is comparing say valverde from 2005 to the current version.

Surely they are more "professional" these days.
 
Mar 13, 2009
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meat puppet said:
^ I don't think its either or but both and when it comes to (microdose) epo and blood transfusions. The transfusion cycle basically requires epo to be effective under a heavy training load.

Refrigerated red cells endure ca four weeks. After that they need to be reinfused. Frozen they can last longer, but some loss of rbcs is expected using this method. It is also more expensive.

As a separate observation..... Watched several editions of amstel and fleche during the week on YouTube from 1999 on. It is quite astonishing how markedly the anthropometry of the riders and the top contenders in particular changes over the years. To wit, they become a lot thinner. This is not something new of course, but the change becomes very pronounced when the footage from 20 or so years is compressed like so. One illustrative example would be the disappearance of riders with body types like bettini from the finales of hilly classics. Another is comparing say valverde from 2005 to the current version.

Surely they are more "professional" these days.

this is why Gerrans was so effective in these decimated sprints like Amstel in the past 6 years, he did not do the lipotropin weightloss, he had all the muscle at his ~66ish kgs, 14lbs give or take at 5'7".

He went from getting his doors blown off by Valverde and Gilbert, to beating them. This off-season, he looked about ~4 lbs leaner, I reckon that is not smart, this route will hurt his terminal velocity. Matthews also lost the weight the last years, then he could hang on the hilly classics, but still get his doors blown off now by Sagan and Van Avermaet.

Remember, Michael Matthews won a bunch sprint at Vuelta, was effective at bunch kicks, placing top 5 in Giro and Vuelta, but does not have the terminal velocity of perennial second place finisher in the bunch kicks Peter Sagan.

The thing about the weight losss, it is a page from Princeton mathematician John Nash' Game Theory which won him the nobel prize in economic. <think> triangulation, compare yourself to all of your competitors, as individuals, and their individual strengths. Gerro maintaining his terminal velocity but managing to hang on the hilly classics, meant he had the finishing speed to win. When before, he had speed, and was competitive in the decimated sprints, but would not be able to beat someone like Valverde, or a Bartoli, or a Rebellin. But then when everyone loses the weight, and does not have the muscle for the explosiveness in the last 5 kms, Gerro starts to win. But he lost a couple of lbs this off-season, but my eye's visual perception.

the lipotropin and the liquid rectal nutrition diet of Team Sky that Race Radio told us about, that means the last ~3lbs, you lean up even more.

This is more than just clen and corticosteroids.

It is a combination of that, but mostly lipotropin, AICAR, GW, and the rectal liquid nutrition inserted straight into the lower intestine. That means the final pounds.
 
Don't know where else to put this, but this is definitely a blast from the past.

My dad was doing some spring cleaning recently, he found an ancient front page of the local newspaper sports section, he had saved it because one of his kayaking buddies was the main story. The paper is from July 2000, prior to the Sydney Olympics, also featured on the front page is Armstrong and Virenque. The title of the article is "French hero Virenque has his day in the sun". Ha-ha!

Unfortunately the article was continued on another page, which my dad didn't save, but at least in the front section it talks about how Virenque beat Armstrong on a climb on the 16th stage of the Tour.

Anyhoo, what a blast from the past, how naive the press and the general public were back then! (Even I was when it came to track and field, other articles in the paper mention Michael Johnson, Maurice Greene, Dan O'Brien, Regina Jacobs - think I'll save the paper just because it gives me such warm, fuzzy and innocent memories.)
 
http://www.bbc.com/sport/winter-sports/39929495
Olympic silver medal-winning speed skater Chris Creveling has been banned for four years after testing positive for testosterone-booster clomiphene.

The 30-year-old American, who won 5,000m relay silver at Sochi 2014, will miss the 2018 Games in Pyeongchang.

He has accepted the US Anti-Doping Agency's sanction, which is effective from 18 November 2016, the date of his provisional suspension.

Traces of clomiphene were found in an out-of-competition test in October.

Clomiphene was initially developed as a fertility drug but has performance-enhancing qualities as it boosts levels of testosterone.

Clomifene at wiki https://en.wikipedia.org/wiki/Clomifene
"It has been found to increase testosterone levels by 2- to 2.5-fold in hypogonadal men."
 
Jul 10, 2009
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Not sure which thread to post this but here goes.

Remember Lance used to come to the dauphine and ride half-baked, we found out later via Tyler that was because they had just off-loaded BB for TDF so there is a kind of performance drag on that. Remember Cadel and Nibs at the dauphine and then wow at the TDF. I am thinking about the recent dauphine and a couple of Riders who seem half baked.

AC seems really half-baked, may have off-loaded a massive BB dump. hey, one last go right?
Froome seems 3/4 baked, is that a small dump because of watchful eyes on Sky? Besides I think Sky has a different program, not sure its BB because their riders have won the dauphine and then won the TDF
Porte knows the sky program, does not look like a dump from him.
Fulsang and Aru coming alive at the dauphine? I wonder with Vino, he demands success but they couldn't have stored, unless they did it earlier.
I do wonder about Quintana and no show between now and dauphine, store? but with the impact from Giro, must have stored something fresh earlier.
 
May 26, 2010
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fmk_RoI said:
Not doping, but I've seen similar spun as doping in the blood doping thread: LottoNL to use blood-testing tech
The device, called Ember, is made by California-based Cercacor Laboratories and tracks hemoglobin and other biomarkers. It was launched last year at the Consumer Electronics Show, but this is the fist time a full pro cycling team, LottoNL–Jumbo, is using the device at the sport's highest level.

sounds to me like they are using it to monitor blood doping.

"a blood-testing technology that almost instantly tells riders how their bodies are reacting to training and racing, and it could change how the world's best bike racers prepare for target events."
 
Phentermine

Doped jockey -
http://www.smh.com.au/sport/horsera...ing-appetite-suppressant-20170629-gx0wx6.html

Melbourne Cup winning jockey Michelle Payne was on Thursday suspended for one month after she was found guilty of taking a banned substance earlier this month.

Payne, who pleaded guilty, told stewards: "I am embarrassed and I apologise for what I have done."

Racing Victoria stewards, after hearing evidence from Payne who was represented by lawyer Michael Rivette, handed down the one-month suspension which will begin immediately.

Stewards told Payne they had received results of a urine sample given by the jockey at the Swan Hill Cup meeting on June 11. They explained that the substance Phentermine, an appetite suppressant, was detected.
 
May 27, 2016
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Re: Re:

blackcat said:
this is why Gerrans was so effective in these decimated sprints like Amstel in the past 6 years, he did not do the lipotropin weightloss, he had all the muscle at his ~66ish kgs, 14lbs give or take at 5'7".

He went from getting his doors blown off by Valverde and Gilbert, to beating them. This off-season, he looked about ~4 lbs leaner, I reckon that is not smart, this route will hurt his terminal velocity. Matthews also lost the weight the last years, then he could hang on the hilly classics, but still get his doors blown off now by Sagan and Van Avermaet.

Remember, Michael Matthews won a bunch sprint at Vuelta, was effective at bunch kicks, placing top 5 in Giro and Vuelta, but does not have the terminal velocity of perennial second place finisher in the bunch kicks Peter Sagan.

I think you channelled stage 3 blackcat