This is going to be a crazy stage. Movi, Bahrain will be very keen to get riders in the break. The start is flat, so I can see that some teams might not be happy with the composition of the break and keep to gap down to provoke a reshuffle on the Mortirolo. Anyway, pretty much for sure Movi and Bahrain will have a couple of riders in front and hopefully FDJ too. Depending on how the Sunweb team is dealing with the situation, the main attacks will happen in the last few km of the Stelvio or early on the Umbrail. On such a parcours, only the strongest domestiques will be able to directly help their team leaders (beyond the initial workover on Sunweb), but Movi and Bahrain have a couple of these. Others have mentioned the Andorro stage in the 2015 Vuelta. It is not a perfect analogy. Dumoulin rode nearly all of that stage under the radar and time-trialled up the final climb limiting his losses to Aru. Now Dumoulin is stronger, but he is clearly the main opposition to anybody wishing to win the Vuelta and alliances of the moment may play a huge role (most likely Pinot and Quintana, Nibali's possible role seems more unclear). Anyway, my prediction is that Tom D loses 1-1:30 to Nairo.
In Andorra my advice to Tom D was to stay under the radar and use the rivalry between the other riders. Since this is now impossible for Tom D, this advice now goes to Landa. Getting into an early break is fine, but let the others fight it out before dealing the killing blow to win the stage.