It would be almost impossible for remco to drop pogacar, van der poel or van aert on that climb. Even attacking by far, he would be followed by then. It would even be difficult for him to beat them on the sprint.
One day races like il lombardia, with more difficult climbs, are more suitable for remco.
While i'm sure he could win a sprint against many climbers or domestiques at the end of a hard day, him sprinting against those 4 would need a miracle for him not finishing last.
Yes, more difficult races would suit him much better. But on the other hand, let's not forget he has won in ways and in races/stages that weren't even that hard, that nobody ever thought would make sense. Let's say QS makes the race as hard as possible, and he does attack early, gets away with an elite group including Pogacar, Van Aert, Van der Poel and some others that could survive Cipressa. If noone has any doms left to work, i could see a scenario where sets an excruciating pace at the foot of the Poggio, form permitting... If he does get a gap, knowing it's him, who is going to do the work chasing him? They will bank on catching him on the downhill, but if he has a 5 second lead after the descent, he's gone.
Which/how many of his presumed goals does he have to win this year for it not to feel like a failure. Is anything less than Giro, Liege, WCTT a bad season for him?
Was this season a failure for Pogacar? He did win Lombardia but that was not the biggest goal.
I think a failure would need him to not be in contention for a big victory at all. We can expect him on the podium of the Giro, but a lot can happen, and not every setback has to mean failure.