- Mar 25, 2013
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olopaine said:Mäntyranta's nephew Pertti Teurajärvi was an olympic athlete in the 70's & 80's, with modest results compared to Mäntyranta. He probably carried the gene though, as it is a dominant gene in the family and as common in men and women.
Mäntyranta's gene mutation and hemoglobin levels come up every now and then when doping is discussed in Finnish media. One question that came up after FIS introduced the 170 Hb level limit, is how FIS would have treated an athlete with a hemoglobin level naturally higher than that.
Yes, it says he had it in the book.
Libertine Seguros said:I haven't read Epstein's book so I don't know if this is old news, but this obituary of Finnish cross-country skier Eero Mäntyranta is quite interesting, and in amid the discussion of Mäntyranta as a person as you might expect from an obituary, there is anecdotal evidence of experiments done to show that Mäntyranta had a genetic condition that made him hypersensitive to EPO (of course his career was many, many moons before the synthetic EPO in sport era so perhaps that aspect shouldn't be lingered on so much as that this experiment could give some insight as to why EPO doesn't affect all competitors equally and give scientists some indicators on what makes someone a super-responder).
It also makes you wonder, how good would Mäntyranta have been had he been around in the 90s?
I read The Sports Gene over the Christmas period and it was my initial reaction as well to this section.
A couple of things:
At times, Eero's extraordinary red blood cell count - measured at up to 65 percent higher than that of an average man.
But when hematologist Eeva Juvonen examined Eero's bone marrow cells in the lab, she saw something astonishing. In order to test whether his bone marrow cells - which produce red blood cells - were particular sensitive to EPO, the research protocol was to add EPO to a cell sample and track red blood cell production. Eero's bone marrow cells began the process of creating red blood cells before Juvonen could even stimulate them with EPO. Whatever tiny speck of EPO that was already in the sample was enough to keep the red cell factories luminating. So it was clear that Eero's body heeded the call of even trace quantities of EPO with extraordinary vigour.
Really enjoyed this book. Great research by Epstein.
EDIT: Just seen that this section is referenced in Libertine's link.
