Argument or not, the winning rider of any generation historically, is always going to be the best rider (with adequate good fortune) most suited to the wider context of cycling of the moment in time, including any doping methods and team structures that apply to its context. If you have a rider taking testosterone, that doesn't tear tendons racing against one that does then clearly the race falls to that rider. If you have a rider with an entire team on their side v one that isn't, chances are obviously against the less structured team.
The whole super-responder myth is just that. To get to a point that some will argue doped donkeys beat doped thoroughbreds is simply a reflection of who you thought deserved to win & nothing else imo. If doping donkeys was the key to winning the sports biggest race, why does every team try and sign the best rider they can afford? Tthey would be better off looking lower down the rankings and save a few $million.
Well except there are innumerable examples to disprove your claims. Teams sign riders at different levels, they don't sign donkeys hoping they can turn them into stars, sometimes it just happens. You think US Postal signed a 27yo Levi Leipheimer from a US domestic team thinking he would be a potential GT contender? Of course they didn't. Leipheimer was signed primarily for small stage races and the US scene
Or Ariostea signed Bjarne Riis(best GT finish 43rd) thinking after 6 years as a pro, he would somehow be a future Tour winner? Of course not. Riis was signed as a solid rider who could maybe do ok as a stage hunter/ond day rider.
Or Mecair signing a 32yo Piotr Ugrumov(best GT finish 8th) expecting him to be a Tour/Giro Runner-up. Of course not. Mecair were a small team who probably signed Ugrumov on the cheap hoping he could give them a GT presence i.e Top 10 or stage win.
The list could go on and on.
Then on the flip side, you have someone like Beat Zberg, same age as Armstrong, first year as a pro finished 4th Dauphine, 5th Tour de Suisse, 6th Tirreno-Adriatico, wins 2 Italian one day races and Etoile de Besseges. Probably his best season in a 15 year career.
There may be other factors involved, but to say riders dont repsond to doping differently is wide of the mark.