Today is Friday, the day of reckoning. A lot of things can be decided in the queen stage.
Girmay can secure his green jersey. Even if Philipsen wins the early sprint, the Eritrean only needs to be in the top 8 to keep a lead of more than 20 points.
The polka-dot jersey is a different matter. There are 20, 40 and 10 points at stake on the three climbs. It's absurd that the Col de Vars is worth twice as many points as Isola 2000, but ASO decided to disadvantage the GC riders. This means that Lazkano, Carapaz or even Gaudu can still win the KoM.
The Cime de la Bonette is a beast: the highest paved mountain pass in France, the highest point in the history of the Tour. Isola 2000 is the second toughest MTF in this Tour. These two climbs were already lumped together in the 1993 Tour, when Rominger won the stage after dropping everybody except Indurain.
It's the last chance for a major GC attack. It can be important to still have at least one teammate with you in the valley, so sending someone up the road might be a good idea. Somebody who has a bad day and gets isolated too soon can lose ten minutes here. The most likely outcome is that the top 3 stays the same, but you never know.