WillemS said:Well, here's a theory, well to not degrade the word any further, let's call it speculation.
After the recent doping busts of several low-level riders caught with GW-501516 in their samples, we can safely assume that at least part of the peloton has changed gear[1] from traditional blood doping, such as EPO, to metabolic modulators, such as GW-50, Telmisartan and Aicar. We also know that different people react differently to different medication, adding at least one additional factor to the genetic predisposition to do well in cycling and other sports. What if this alone might cause a shift in dominance between top riders. It might not be unreasonable to think that the odds are that there is no single rider that benefits the most from every variety of PEDs.
From what I've read on fora related to the use of doping (e.g., bodybuilding fora), GW-50 seems a great drug to enhance overall endurance, but, if used to enhance endurance maximally, might actually inhibit sudden bursts of high power needed in heavy weight lifting or, for instance, pure anaerobic sprints. In the bodybuilding community, this is mainly explained by a shift of metabolism to and increase in aerobic mechanisms, such as fat burning (main reason for bodybuilders to use the drug)[2]. In short, it might favor those riders with a riding style of continuous high watts (ala Sky-train) in stead of those with the ability to maintain high anaerobic attacks for a greater period of time than the rest (ala attacking with two to three km's to go, like Contador used to do).
Remarks
[1] "Gear" is often used on fora discussing the use of PEDs as a term for those PEDs, such as steroids and, more recently, SARMS and other peptides. Might those "gear problems" given so often these days after a bad performance be a euphemism for selecting the wrong drugs? I think not, but I can't help thinking that every time a rider is quoted saying something like that.
[2] Some anecdotal evidence, stories from GW-50 users on steroid websites, seem to suggest that the user might maintain aerobic metabolism at higher heart rates than usual, but were sometimes unable to use glucose as a fuel. This remind me of De Gendt saying that he was getting dropped on a climb with a very high heart rate, but not feeling very much pain or a feeling of being wasted. Oh, well, speculation. There are so many possible explanations...
Miburo said:What was the vuelta 2012 then? Don't be idiotic...
I hope he'll visit some doctor. Better a chance getting caught than having this ****.
The Hitch said:You don't care about his personal health? What if he and Macarena want to have children. It's sad that in modern cycling people are put in these positions where they have to play Russian roulette with their health to reach their potential and I can understand why they tak the decision under the circumstances but no way it is still the wrong thing to do and the dumb thing to do
The Hitch said:You don't care about his personal health? What if he and Macarena want to have children. It's sad that in modern cycling people are put in these positions where they have to play Russian roulette with their health to reach their potential and I can understand why they tak the decision under the circumstances but no way it is still the wrong thing to do and the dumb thing to do
Galic Ho said:He is 30 not 29. 31 in December.
Same age Evans was in 2007. Think about that for a second people. He's got plenty of years filled with GT wins ahead of him.
jilbiker said:Will he risk it and juice for TDF? I doubt it, its way too late.
jilbiker said:Just read on Wikipedia about GW501516 " The drug was discovered to cause cancer in rats and GlaxoSmithKline has ceased development". Thats amazing what these folks put themselves through all for an extra buck. Cancer causing drugs, Blood bags, injections in the scrotum and who knows what else. Horrible! Horrible!
Exactly the info I needed, tyGregga said:Because the red cells live about 30 days, and because you have to recover from the extraction, they often gave their blood just before or just after the Dauphiné, according to Hamilton.
But that was the old method, more than ten years ago, in 2004 Fuentes started freezing the blood bags, in that case, the BB's can be used months after the extraction, which is no more the cause of underperforming like Contador today.
IMO, he's simply on zero blood doping this week, keeping his blood stocks for the Tour and not able any more to use EPO microdoses because of the new testing protocol. The remaining question is "what the Sky are on" ?
We never saw anything from basso after the giro? Well he was getting on in age. And bare in mind that the next season as he was peaking for the tour this happenedjilbiker said:Contador's performance this season is consistent with riders in post doping suspension era. They can't seem to find that killer touch any more. His win at the Vuelta 2012 was similar to Ivan Basso's Giro win post his suspension. After the Giro we never heard anything significant from Basso. AC is doing his best this season, I don't buy the sick excuse from Saxo, his best doesn't cut it.
I say this is a bread and water AC and the truth is that it doesn't cut it, the peleton is still on PED. Will he risk it and juice for TDF? I doubt it, its way too late.
Tom T. said:Please explain. A doped Contador was clearly untouchable in years past. Are you saying he was previously doped against a clean or less-doped field and now they're catching up to him doping-wise? That's not plausible.
On their bikes 6 hours a day. What are you on.Gregga said:Because the red cells live about 30 days, and because you have to recover from the extraction, they often gave their blood just before or just after the Dauphiné, according to Hamilton.
But that was the old method, more than ten years ago, in 2004 Fuentes started freezing the blood bags, in that case, the BB's can be used months after the extraction, which is no more the cause of underperforming like Contador today.
IMO, he's simply on zero blood doping this week, keeping his blood stocks for the Tour and not able any more to use EPO microdoses because of the new testing protocol. The remaining question is "what the Sky are on" ?
WillemS said:Well, I've also posted this in another thread about Contador, but it's relevant here.
Different people react differently to different kinds of medication, so your comparison with the past does not hold. What we are witnessing is a paradigm shift from blood doping to metabolic modulators as blood doping is getting more and more detectable with the introduction of the blood passport. In comparison to blood doping, metabolic modulators hardly change the blood profile thus rendering the traditional blood passport useless.
What we see is that other people might benefit more from the current generation of PEDs than Contador. I'm not at all surprised that with the shift from blood doping to metabolic modulators (such as GW-501515, Telmisartan, & Aicar), we see a shift of balance in rider dominance. Different people react differently to different kinds of drugs.
I've added some speculations to this ones in another post, here.
Gregga said:Because the red cells live about 30 days, and because you have to recover from the extraction, they often gave their blood just before or just after the Dauphiné, according to Hamilton.
But that was the old method, more than ten years ago, in 2004 Fuentes started freezing the blood bags, in that case, the BB's can be used months after the extraction, which is no more the cause of underperforming like Contador today.
IMO, he's simply on zero blood doping this week, keeping his blood stocks for the Tour and not able any more to use EPO microdoses because of the new testing protocol. The remaining question is "what the Sky are on" ?
Pulpstar said:Here in the UK alot of people voluntarily (myself included) give blood donations voluntarily to help out. Putting a wild idea out there, perhaps each registered Grand Tour rider could give a pint 6 weeks or so before the start of each Grand Tour. Physiologically they'd be recovered by then and you certainly wouldn't want to double dip on an extraction as that would be wildly dangerous and performance dropping I'd imagine.
It's in French. Could you or someone else give some more info about what is in there.Parrulo said:http://www.velo-club.net/prntopic.php?forum=3&topic=58788&post_id=1872572
Credits for this go to Roundabout who posted it on the RR section. Anyway this guy says that Contador's numbers are fine and all that.
But what truly matters about this is that it seems like AFDL are all over Contador even testing while he was doing reckon. Interesting imo.
Parrulo said:http://www.velo-club.net/prntopic.php?forum=3&topic=58788&post_id=1872572
Credits for this go to Roundabout who posted it on the RR section. Anyway this guy says that Contador's numbers are fine and all that.
But what truly matters about this is that it seems like AFDL are all over Contador even testing while he was doing reckon. Interesting imo.
The Hitch said:On their bikes 6 hours a day. What are you on.
WillemS said:Well, here's a theory, well to not degrade the word any further, let's call it speculation.
After the recent doping busts of several low-level riders caught with GW-501516 in their samples, we can safely assume that at least part of the peloton has changed gear[1] from traditional blood doping, such as EPO, to metabolic modulators, such as GW-50, Telmisartan and Aicar. We also know that different people react differently to different medication, adding at least one additional factor to the genetic predisposition to do well in cycling and other sports. What if this alone might cause a shift in dominance between top riders. It might not be unreasonable to think that the odds are that there is no single rider that benefits the most from every variety of PEDs.
From what I've read on fora related to the use of doping (e.g., bodybuilding fora), GW-50 seems a great drug to enhance overall endurance, but, if used to enhance endurance maximally, might actually inhibit sudden bursts of high power needed in heavy weight lifting or, for instance, pure anaerobic sprints. In the bodybuilding community, this is mainly explained by a shift of metabolism to and increase in aerobic mechanisms, such as fat burning (main reason for bodybuilders to use the drug)[2]. In short, it might favor those riders with a riding style of continuous high watts (ala Sky-train) in stead of those with the ability to maintain high anaerobic attacks for a greater period of time than the rest (ala attacking with two to three km's to go, like Contador used to do).
Remarks
[1] "Gear" is often used on fora discussing the use of PEDs as a term for those PEDs, such as steroids and, more recently, SARMS and other peptides. Might those "gear problems" given so often these days after a bad performance be a euphemism for selecting the wrong drugs? I think not, but I can't help thinking that every time a rider is quoted saying something like that.
[2] Some anecdotal evidence, stories from GW-50 users on steroid websites, seem to suggest that the user might maintain aerobic metabolism at higher heart rates than usual, but were sometimes unable to use glucose as a fuel. This remind me of De Gendt saying that he was getting dropped on a climb with a very high heart rate, but not feeling very much pain or a feeling of being wasted. Oh, well, speculation. There are so many possible explanations...
Gregga said:IMO, he's simply on zero blood doping this week, keeping his blood stocks for the Tour and not able any more to use EPO microdoses because of the new testing protocol. The remaining question is "what the Sky are on" ?