Yes, but Nibali did so after Contador and Froome crashed out, so there, had they continued in the race, it's obectively difficult to argue the Italian's victory would still have been of such large time gaps to 2nd and 3rd (if he would have won at all).
On big contenders crashing out, I can think of mainly Alaphilippe. And as Lefevere has stated Julian would have ridden to set up Remco, because they knew how strong he was in working for Ala at FW and the way his legs were turning on the day. What's taking place with Remco's exploit yesterday is unreasonable. Basically some are questioning the feat as such, by arguing that the absence of the top favorite or contenders with inadequite condition makes it less impressive. But this negates an undeniable truth, namely to do what Remco did simply recquires balistic legs, however you look at it, which has nothing to do with who was or wasn't there or in what condition. He simply went into turbo mode in a similar, but differnet way, as Pogacar did on the miserable slopes of the Cole de Romme. Both are exploits in the absolute sense. Was Pogacar's any less exceptional because Roglic was already out, Bernal not in the race and "only" done against Carapas and in the face of a mega-funded Ineos? No and neither was Evenepoel's escape any less sensational.