First EPO users in the peloton?

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Aug 9, 2012
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esafosfina said:
Just to clarify 'doping labratory'... do you mean a lab that tested (ie; anti-doping) or a lab that offered 'assistance' in all its forms?

A lab that offered assistance. It was mentioned by Dag Erik Pedersen in a norwegian article in VG from a few years ago.

http://www.vg.no/sport/artikkel.php?artid=10041070

Needs google translate if you don't speak Norwegian.

It's only mentioned in passing. I'we tried to search for any mention of such a lab, but all I get is an electronics lab in eindhoven.:(
 
Oct 18, 2012
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Nice Lanark! The epo issue was mentioned in the Calgary Herald, do they also have an archive like you have?

The oldest studies on the use of epo by athletes in the pubmed database date from 1988 (some of the University of Ferrara haha) The use in endurance sports was known at that moment,

I think in the mid-80's the first experiments by indivudual athletes were done. Probably not in cycling but cross-country skiing or speed skating.

ToreBear,
Pharmaceutical company Organon was situated in Oss, not far from Eindhoven and Eindhoven has a university.
 
Oct 18, 2012
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Hi Everyone, this is my first post after having lurked for a while following the LA debacle, so go easy...

I was prescribed EPO for medical reasons in 1991, I think it was around Spring. I was being treated in the UK (NHS) and they had limited supplies at that time and could only give it to a very small number of new patients per month. I think they said at the time it was £9k (may have been £6k) for a course. That was a lot of money at the time. I'm not sure how readily available supplies would have been for professional riders, I think they would have required a corrupt contact at the supplier or connections with someone with access to the pharmacy at a hospital (i.e. they would have to steal it). Whichever way you stack it up someone in the chain would have been breaking criminal law.

I personally think the 5% performance improvement is understating it. I had very low haemoglobin at the time due to failed kidneys (on dialysis) and it was a miracle drug. Within a week of starting I was back to normal, if not better than normal. The hospital kept a close eye on my haemoglobin levels as EPO thickens the blood and pushes up blood pressure.

I can say from experience that survivng cancer has almost nothing to do with mental attitude, it is down to getting effective medical treatment. Lance is like one of those fake religious preachers, I don't even think he believes what he says. Livestrong was a very effective cover for his multifarious immoral activities.
 
Apr 21, 2012
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Lanark said:
Peter Winnen wrote an opinion piece last saturday in which he said that he thinks EPO was first used in the peloton in 1988. He says that was the first time that non-climbers started to overtake him, and talking with some colleagues there were some strong hints to what was causing this miraculous transformation.

Great information. I personnaly think Rooks and Theunisse were among the first during the 88 TdF, Winnen's quote could confirm this.
 
Aug 9, 2012
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Totilas said:
Nice Lanark! The epo issue was mentioned in the Calgary Herald, do they also have an archive like you have?

The oldest studies on the use of epo by athletes in the pubmed database date from 1988 (some of the University of Ferrara haha) The use in endurance sports was known at that moment,

I think in the mid-80's the first experiments by indivudual athletes were done. Probably not in cycling but cross-country skiing or speed skating.

ToreBear,
Pharmaceutical company Organon was situated in Oss, not far from Eindhoven and Eindhoven has a university.

Hmm this would be more a scandal that would be widely publicized.

2. How widespread was doping when you were active?
- It was very common in the late 1980's. There was for example a doping laboratory in Eindhoven which was constantly ahead of the testing.
http://translate.google.com/transla....no/sport/artikkel.php?artid=10041070&act=url

I cleaned up the translated mention of the lab.
 
Aug 9, 2012
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losenotaminute said:
Hi Everyone, this is my first post after having lurked for a while following the LA debacle, so go easy...

I was prescribed EPO for medical reasons in 1991, I think it was around Spring. I was being treated in the UK (NHS) and they had limited supplies at that time and could only give it to a very small number of new patients per month. I think they said at the time it was £9k (may have been £6k) for a course. That was a lot of money at the time. I'm not sure how readily available supplies would have been for professional riders, I think they would have required a corrupt contact at the supplier or connections with someone with access to the pharmacy at a hospital (i.e. they would have to steal it). Whichever way you stack it up someone in the chain would have been breaking criminal law.

I personally think the 5% performance improvement is understating it. I had very low haemoglobin at the time due to failed kidneys (on dialysis) and it was a miracle drug. Within a week of starting I was back to normal, if not better than normal. The hospital kept a close eye on my haemoglobin levels as EPO thickens the blood and pushes up blood pressure.

I can say from experience that survivng cancer has almost nothing to do with mental attitude, it is down to getting effective medical treatment. Lance is like one of those fake religious preachers, I don't even think he believes what he says. Livestrong was a very effective cover for his multifarious immoral activities.

Thanks! I think the price of EPO is something that one has to take into account when finding out who used it first. New drugs are expensive, so supply issues are likely to be huge.

My impression is that the epo effect is much more than 10%. But it ofcourse depends on the time period due to the introduction of the hematocrit limit in 1997.

As for positive thinking. If I had cancer I would prefer good medical treatment and positive thinking over good medical treatment and negative thinking. Optimism has a benefit, but it is not easily quantified in studies.

I don't think you should view that as relating to Lance.

Welcome to the forum btw, I'm a newbie too, so I can't guarantee the old timers will be nice to you. They'we been nice to me though.:)
 
Aug 11, 2012
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Gregga said:
Great information. I personnaly think Rooks and Theunisse were among the first during the 88 TdF, Winnen's quote could confirm this.
Well Winnen was talking about non-climbers.

You can say a lot of Rooks & Theunisse but they could handle a climb.

I'm curious which riders Winnen is refering to, because I dont see a whole lot of people who suddenly turned into something special around '88.

Winnen himself was definitely not the same anymore compared to 1981-1983.
 
Aug 9, 2012
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Rob J. Pluijmers, a sportsmedicine doctor involved with Dutch cyclists for 15 years, admitted last week in Salt Lake City that he knows three professionals taking EPO, a recombinant hormone used to treat anemia. He refused to name the athletes, but this is the first official acknowledgement that athletes are using the drug.

Pluijmers, however, denied that any of the 15 deaths could be attributed to erythropoietin.

"There is no reason to think EPO use is involved," said Pluijmers who was visiting the United States to speak to colleagues at the American College of Sports Medicine.

Pluijmers said the cyclists he knows using the drug are from the Netherlands and Belgium. He said the three got the drug from sources in Belgium. One athlete, he said, was taking the drug to treat a medical problem, but the others were using it to enhance performance.

EPO is not yet registered in the Netherlands, although it is widely approved throughout Europe. The Food and Drug Administration approved its use in the United States last June. Amgen, a Thousand Oaks firm, developed the drug here.

Three years ago, physicians and pharmacologists stated their concerns about the abuse of erythropoietin among athletes such as cyclists and distance runners who would benefit from blood doping.

In October of 1989, Dr. Bjorn Ekblom of Stockholm's Institute of Gymnastics and Sport, reported that eight Swedish athletes increased their endurance by 10% after using erythropoietin during a study.

http://articles.latimes.com/1990-06-02/sports/sp-143_1_performance-enhancing-drug

Don't know if this article is posted earlier in the thread, I can't remember it anyway.
 
Aug 11, 2012
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Gregga said:
Great information. I personnaly think Rooks and Theunisse were among the first during the 88 TdF, Winnen's quote could confirm this.
Well Winnen was talking about non-climbers.

You can say a lot of Rooks & Theunisse but they could handle a climb. Winnen & Rooks admitted doping abuse in the same tv program.

I'm curious which riders Winnen is refering to, because I dont see a whole lot of people who suddenly turned into something special around '88. Now if you
compare this to the 90s....

Winnen himself was definitely not the same anymore compared to 1981-1983 though.
 
Jul 8, 2009
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I don't have any evidence, but the use of a new drug that increased oxygen carrying capacity first came to my attention in spring 1989. I heard about it from other distance runners, who claimed that some European runners attending U.S. universities had recently started using it. At that time, I don't remember hearing the name EPO, but then again, I didn't actively seek out more info. I think I first heard EPO a couple years later, at which point it was widely known to be used in distance running circles.

Again, this is just anecdotes, not hard evidence. But I'm convinced that if amateur distance runners were using it, pro cyclists sure were. By 1991 when it was well-known among runners, I'd be absolutely shocked if use among pro cyclists wasn't pretty extensive.
 
Jul 10, 2009
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Like someone on the first page of this thread stated, the first user is probably dead.

Before doctors were telling riders how to use it properly, guys were turning their blood into sludge. I remember reading more than one article in VeloNews during the late '80s through about '91, pertaining to Dutch riders keeling over and dying. No autopsies were performed, they just got these guys in the ground.
 
Oct 18, 2012
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ToreBear said:
Rob J. Pluijmers

Was the doctor of the Buckler team in the eighties.

74005-620-465.jpg


"While sports doctor Rob Pluijmers (in front) a blood sample from Mieke Hawk (l) investigates, she is kissed by her husband Wim Hoogendoorn...(for) the results of a test for the improvement. Mieke hopes in Mexico's to take over the record of Jeannie Longo ." (1987)

What connection are you thinking of? Edit: I understand was in the 80's also a researcher for Organon.
 
Jun 21, 2009
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Highly interesting thread.
Lots of interesting posts. And interesting to see the bias for different riders come out too sometimes.

Read the whole thing... a few comments and questions.

Gewiss 94. That was clearly a further jump. What exactly did they do differently than before? Can't have been the first to use, clearly, but they very very clearly had a huge advantage over the rest of the peloton that year. Just more? Or the first ones to really use it effectively, or as a team? Thge rest then followed suit in 95?

Then disagree a bit with the occasional "the doctors are devils" sentiment. Guys like Ferrari etc. just simply know what they are doing. No Ferraris around and you have more doping deads around, that simple. Guy with an IQ like Riccò and EPO around without more info on how to use it and he's dead in 3 days. Self policing of teams and riders was clearly there too, mentioned here, or see Järmann's confession. (Still IMO one of the most valuable confessions, since it came out of nothing, no special suspicion of him, he had retired and could have just kept silent) First confronted with EPO in an Italian Team (Ariostea obviously, since he only rode for Feretti in Italy), not forced, he says the team docotor informed them about EPO, what it did, mentioning that all others were already using it. He says that internally they put the limit at 48%. Then up to 50% a year later, and then 52% a year later again. He himself probably started using it in 95. Or 96, not very clear there. He still won Amstel clean in 93, a Tour stage in 92, so very likely around then EPO wasn't that widespread yet, not used to it's max yet, (not only at Ariostea, but other teams too). The link to his confession: http://www.jaermann.ch/Tagebuch/Doping.pdf

First GT winner with EPO?
Doubt it's in the 80es somehow. Might be wrong, no clue really. But again, until Gewiss and Riis in 93 (the first year he suddenly was in the GC, before he was a mule. Or imaginable as a stage chaser, never a GC contender) somehow everything seems more normal not only at the time, but in retrospect too.
Some names thrown around:
- Bugno. He was considered a huge talent in Italy. But yes, his 90 Giro was much stronger than could be expected, I for one never thought he would ever win a GT. More of a classic guy than a GT guy...(but then I never liked him, so biased on that one)
- Chioccioli 91. Possible, but he certainly wasn't a mule. He had shown GC potential at the Giro since his earliest participations, just never enough. The last step with EPO though is certainly possible.
- Chiappucci. Ok, never won anything, still put him in here: He came out of.. almost nothing. Not completely nothing.. he had a serious injury early on in his career, a parked car on a downhill in the TdS. Then showed some potential... but not really all that much. 90 TdF itself wasn't that surprising then I thought. Good Giro before, and with a 10' advantage he had something to fight for, thought that what he then showed in 91-92 was almost more surprising.. According to his wiki page he later said he took EPO from 93 on...later retracted it. Doesn't mean wasn't earlier. looks suspiciously like defending his good results as clean.
- Rominger: Likely he was on EPO for all his GT wins. But he certainly wasn't a mule either. Ok, might be biased, since I'm swiss, but he was regarded as a guy with very high potential already before that. The swiss press expected him to fight for the win in 90 or 91 too, he failed miserably there. But IMO not a mule.
-Indurain... see Rominger for the EPO probability. But he had been tipped as a future Tour winner for years. After 90 newspapers were full of "was a mistake to have Delgado as leader". So.. 91 he might have been on EPO, but I wouldn't bet my life on it, after all Mottet who is regarded as clean still came in 4th. Later on of course for sure, for 91, don't really know, but could still imagine him being EPO less. But anyway, seeing the jump by Riis in 93 and the GEwissjump in 94 it seems likely that even if he was on EPO, it was a smaller dosis.

Not mentioned much here:

Giovannetti: Vuelta 90. I'd say good chances of being clean (of EPO) He had shown GC potential all his career, here profited from an escape, defended it, which seemed fully within his potential. A surprise winner, but with the escape present not really anymore.

Mauri: Vuelta 91. While Bugno 90, Chiappucci 90 and others could be very well possible too... he just looks like a clear EPO Baby. Really out of nowhere, compared to him Chiappucci in 90 was a superstar... Beating Indurain everywhere in TTs....

80s.. .very very likely some guys were on it, like that Hermans guy somebody mentioned. The big guys... of course possible too. Even if of the winners nobody looks really suspicious, nobody who couldn't have done it without EPO. Interesting guys like Giupponi. 5th, 4th, 2nd from 87-89 in the Giro then never could played a role again really. Best then 11th in 93. Early EPO user? Or clean guy that then was a victim of others EPO? Somehow both seems possible. First Giro in 86 as a Neo 43rd, but seems to have had success as an amateur, Valle d'Aosta, Giro delle Regioni

But anyway, to me the performances that just seem VERY clearly a result of early or stronger dosage of EPO
- Mauri
- Riis from 93 on
- Gewiss 94

Higher dosage than others at the time, or generally better usage, don't know, but that's the 3 performances that were completely unexplainable, or lets say barely explainable without a wonderdrug at the time.
 
Sep 21, 2012
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CN article: Armstrong's fraud paralleled EPO-makers' feud talks about a soon-to-be released book titled "Blood Medicine: Blowing the Whistle on One of the Deadliest Prescription Drugs Ever"

... "In Europe, EPO's clinical trials began, and marathon runners, Nordic skiers and Dutch cyclists were getting a hold of the drug on the black market. From 1987 to 1990, about 18 young cyclists died under mysterious circumstances, including 27-year-old Johannes Draaijer."
 
Aug 27, 2012
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First use would likely have been Amgen related as they held the patent and early production exclusive. From 1985. So probably via Eddy B's team which included Armstrong.

Interesting to relate this to LA's questioning of Greg Lemond's victories (last one 1986) insinuating EPO use, and Greg's answer. Maybe LA simply did not know Eddy was the first one world wide with access, through Thom Weisel...
 
Jan 7, 2012
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Tinman said:
First use would likely have been Amgen related as they held the patent and early production exclusive. From 1985. So probably via Eddy B's team which included Armstrong.

Interesting to relate this to LA's questioning of Greg Lemond's victories (last one 1986) insinuating EPO use, and Greg's answer. Maybe LA simply did not know Eddy was the first one world wide with access, through Thom Weisel...
In the mid '80 I and several of my friends looked closely at investing in Amgen. At that time, the biggest concern regarding EPO (which was one of 5 promising developments at Amgen) was the prospect that a rival company would develop a similar oxygen vector which wouldn't be covered by the Amgen patent. Recall that EPO itself is a naturally occurring substance, and isn't patentable. The process to make recombinant EPO is. Amgen had a US competitor with a plausible claim to the patent, and it was generally believed that several European companies had substantial R&D efforts. Furthermore, it was believed that the European companies were using athletes to evaluate the efficacy of their potential products. Amgen didn't need to do this, because they already had trials in process, whereas the European companies needed to avoid public disclosure--otherwise they could expect lawsuits from Amgen. Amgen of course knew that these irregular trials were going on, but as long as the info wasn't public, they couldn't practically go after the European companies.

At least that's what we believed at the time, but it was a pretty widespread belief. It raises the interesting possibility that riders were using EPO-like drugs during say '85-'87, but which were less effective than Epogen. The when Epogen became legally available, they may have believed that ever larger doses would be better, and folks started dying.

Anyway, from what I remember, and from the known deaths in cycling as well as soccer, etc, I think it is more likely that the introduction of illicit use of EPO was in Europe.
BTW, LeMond's last Tour victory was in 1990.
 
Aug 27, 2012
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Thanks for post. You have refreshed some of my deep memory of the early EPO drug development era. And GLM TdF victories.
 
Jun 25, 2009
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In the Finnish TV documentary "when Heroes Lie" - XC skier Erja Kuivalainen spotted EPO before Lathi Worlds in 1989 on Marjo Matikainens hotel-room table. This would be late 88 or very early 89.
 
Oct 12, 2012
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experiments on obtaining natural EPO from urine for example started in 1977. 1987is significant because in that year they were able for the first time to synthesize EPO.

Although no real autopsy was done on the 18 dutch and belgian cyclists that died and were contributed to early EPO use (autopsy would not really have helped since there was no test for EPO) the case of Johannes Draaijer is significant as his wife told Der Spiegel (leading german magazine) that her husband got sick and died after takeing EPO.

take into account though that in 1988, the first rider was banned for using EPO. (http://autobus.cyclingnews.com/results/archives/jan97/25_1.html)
 
Jun 12, 2010
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bobbins said:
I've heard it was first available in 1987.

What significant happened that year?


Stephen Roche won the TDF..Giro and World Champs. He never came close to repeating that kind of form. In the 90,s an Italian court concluded Roche and others on the Carrera team were adjudicated to have been using EPO under Conconi,s guidance from 93 >.
This all begs the question was Roche possibly using EPO in 87 ?..though I suspect blood banking more likely.
 
Aug 12, 2009
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Darryl Webster said:
Stephen Roche won the TDF..Giro and World Champs. He never came close to repeating that kind of form. In the 90,s an Italian court concluded Roche and others on the Carrera team were adjudicated to have been using EPO under Conconi,s guidance from 93 >.
This all begs the question was Roche possibly using EPO in 87 ?..though I suspect blood banking more likely.

whilst I wouldn't rule it out...roche relied on a high degree of luck to compile that triple...he wasn't dominant in the tour relying on a final tt victory and a daring plunge from the col de joux plane to extract time from delgado. The gir was only achievable thanks to the bold Robert Millar and Schepers 9although arguably his best form of the year) and the worlds was an opportunist win from a group of (around 12ish) equally strong riders....

besides it was an odd year and he always did well in odd years (81, 83, 85 and 87) :)
 
Aug 11, 2012
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gillan1969 said:
whilst I wouldn't rule it out...roche relied on a high degree of luck to compile that triple...he wasn't dominant in the tour relying on a final tt victory and a daring plunge from the col de joux plane to extract time from delgado. The gir was only achievable thanks to the bold Robert Millar and Schepers 9although arguably his best form of the year) and the worlds was an opportunist win from a group of (around 12ish) equally strong riders....

besides it was an odd year and he always did well in odd years (81, 83, 85 and 87) :)
Exactly the TDF of '87 could have won by a few riders.

He was not dominant in the Giro either and had his fair share of injuries (knee) between 1988 and 1991. Having said that, he was a good rider who could win one GT in the right circumstances (like '87).

Anyway, too many arguments to even think that Roche used EPO in 1987.

1992 and 1993 is a different story though...
 
Mar 17, 2009
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skimazk said:
experiments on obtaining natural EPO from urine for example started in 1977. 1987is significant because in that year they were able for the first time to synthesize EPO.

Although no real autopsy was done on the 18 dutch and belgian cyclists that died and were contributed to early EPO use (autopsy would not really have helped since there was no test for EPO) the case of Johannes Draaijer is significant as his wife told Der Spiegel (leading german magazine) that her husband got sick and died after takeing EPO.

take into account though that in 1988, the first rider was banned for using EPO. (http://autobus.cyclingnews.com/results/archives/jan97/25_1.html)
Name of said banned athlete? A little difficult to ban someone fora substance that wasn't prohibited until 1990.