I'd be surprised if he does confess, although at this point perhaps he's got no choice, especially if the fed case re-opens against him.
People that say, however, that LA was only doing what everybody else did, don't know the facts. He didn't pay Ferrari 1 million dollars for nothing (to only work intimately with him during his Tour streak, for example). One of the things that Hamilton's book clarifies, is that at the point at which he started to do transfusions on Postal, Lance was already privileged to this treatment for some time before anyone else on the team. Hamilton also believes that LA had sole access to a synthetic blood. In short, LA didn't just look to win on the bike through doping, but also win the doping arms race, by staying ahead of the game and this is how he gave himself a nearly unbeatable edge.
Moreover, he slandered many and ruined others: this from riders like Bassons to Simeoni, to Betsy and Emma, to Walsh - for his book LA Confidential - whom he sued and won, to Kimmage, to ruining Lemond's bike business with Trek. To say nothing of having the collusion of the UCI and ASO.
So, no, he wasn't just an average doper, but a privileged and protected egomaniac. He worked the system and doping regime greater than anyone, while tried to, and in many cases did, ruin anyone who got in his way, making punitive strikes if he even suspected that another rider was up to something he wasn't. Such was his paranoia of being outdone in cheating. Hamilton's book also brings this to light.
How good of an athlete he actually was will never be known, because he never saw sport as anything other than "you dope to win." It now seems certain that already as a teenage tri athlete he was doing steroids. He thus had a doping regime accompany him his entire sporting career. He simply didn't know how to play the game any other way, couldn't even contemplate performing clean, which in his own words was for idiots and losers; because if you didn't compete to win, win, win, you were either an idiot or a loser (and probably an a-hole too), or both. For LA, though, it wasn't just about doping, but doping better than anyone else, for which, again, he was always paranoid about being outdone. Although it was just that, his paranoia. He obtained such a name for himself and so much power in the sport, that he got the best treatment this and his unrivaled earnings could buy and most likely was given new drugs only he had access to in the beginning. Nobody was going to beat Armstrong at doping, this was what really transformed him (not cancer) into becoming the ex-greatest Tour rider ever. So he was the best doped athlete, which of course has nothing to do with being the best athlete and, besides that, a world class cynic and liar. Nobody could outdo him in these categories either, not in being cynical, nor at lying, or at being ruthless.
The only thing worth hearing his confession for, would be if he were to provide details on how he was able to stay one step ahead of the competition in this regard. What new stuff was he on and who were his sources of info./providers?