Wouldn't surprise me if the Rams-Niners game has even fans. LA is a good sports town, but it's also very hodgepodge, people from everywhere.
Like I said, on paper, the Rams have the players, tools, experience, QB, home field, to beat the 49ers. This logic, plus the 49ers record, Garappolo's own habit of mistakes, and the Rams should win by a score of about 27-17. But looking at the last 11 weeks of the season, here's something telling about the Niners:
During that stretch, the 49ers are 9-2, including two wins over the Rams. The only games they lost were Seattle 30-23, and Tennessee 20-17. The rest of the schedule was a mixed bag and they didn't blow anyone out, but they did beat the Bengals in that run. I didn't do an average, but their defense is only giving up about 20 points a game. In recent games their D has really stiffened up, giving up a total of just four TD's in the last 10 quarters, against the likes of the Rams, Cowboys, and Packers, all on the road.
This game, especially if the 49er defense is on, the game is close, or they start making any mistakes, could really get into the Rams heads. As likely as the paper says they should (finally) win, it doesn't take much imagination seeing the Niners playing a solid game and walking away with a victory, regardless of how many mistakes the Rams make, and it's their habit to make them.
Also, as JM Dirt says, as the game goes on, the 49ers seem to get stronger, the Rams, with their lack of depth, and big money on older players, gets weaker.
Another interesting thought is that I think the 49ers could win the Super Bowl. I don't see the Rams beating either the Bengals, or especially the Chiefs.