I think they have to try to continual try to get men into the break to force Sky to have to chase as much as possible over the next few stages. And once the break is established, they have to attack on EACH climb. Make Sky react; keep them off balance. Crank up the pace when Sky is in some kind of lull, distributing food, etc. Sitting back and waiting for the last mountain of each stage, with that last long ITT looming, is pure fools gold. Frankly, I'm surprised that neither were more opportunistic during the first week. Now they have to be. Also, before I forget, make Sky chase all attacks. If Nibbles attacks, don't follow, wait for Sky to react. When they cover, then someone else attack. Rinse repeat. They want a steady rhythm. Don't let them have it. EVER.
All that being said, I don't think any of the other "contenders" (and I use that term lightly) will look beyond their own self-interest and will look to consolidate their position (Cuddles) or only aim for podium (Nibali et al). This is why I miss AC. I know he would attack and attack and look for time wherever he could. I don't have that sense of any of the other remaining "contenders." Hopefully I'm wrong (Nibali never gave up in the 2011 Giro, nor Scarponi, hopefully they remember that).