Lance's position as the visible leader in the "war on cancer" is why he has transcended his sport, that much is easy to see. It is his stature and visibility that has helped deliver him to the US, and to a lesser extent the world, households. It is his "doing good" endeavors that perch him at the apex of a kind of wholesomeness blended with work ethic and determination that when matched with all his athletic feats, morphed him from a champion cyclist to a celebrity that has eclipsed almost any other US athlete.
It is all of this, and the underlying trust and integrity that his faithful have attributed to him, that will be his undoing. His willingness to have such a disparity between the "truth" and the "brand", going to extreme means to coordinate and manage what was essentially the best doping program in sports all the while campaigning on a platform of "never doped" that will leave his truest followers conflicted and betrayed.
I think the differences with Vick, and I realize it was just a handy example, are too great to make any meaningful comparison. Vick acted a thug, gave women STD's and despite being blessed with terrific athletic skills was never a real champion. He was not a champion for a cause and basically, as far as I can research, did the minimum to keep his job secure(which he now admits).
Lance is at risk across the demography, middle class "avg Joes", soccer Moms, upper class professional men, young kids who latch on to the image and the myth, and also the real hardcore followers: The people afflicted with cancer and their loved ones. Finding out it was a massive lie, that the guy doped to win and boldly proclaimed he was clean will cut deeply. These folks will react badly to his betrayal. It will hurt a lot. I think they will care a lot. Violation of trust like that is pretty serious emotional wreckage.
I don't see some Vick-like bounce back because his lie was not tied to his work or athletic job, and it was not tied to pandering false hope on the back of a very massive fraud. Vick lied about his "hobby", and that is not to downplay killing dogs, which I find morally reprehensible and disgusting. It is just very different than Lance and his false world.
I see Lance in a no-win situation. He is at risk of having some serious crimes leveled at him, ones that will require the exposure of the fullness of his scam to prove. It is narrow-minded to think these authorities won't get cooperation from the teammates, or from employees, or his ex-wife. It is a simpleton's view to think they won't roast him and his henchmen under the pressure of a very serious trial. They will and it will be very ugly and difficult for Americans to digest. He was their hero and he preyed on their emotions with devastating effectiveness thereby gaining their trust all while shielding himself with a cancer charity, making him "untouchable". You question him, you question the whole of them. How can so many people be wrong about their hero? He's Lance!
When it all breaks, there will be a massive lash back. I don't think his sponsors will be long by his side. Maybe Trek and Oakley, since they are the closest to him and cannot claim any level of ignorance as to how he came to win the TdF 7x. The reaction from fans will make him a very publicly ridiculed person. It will be abandonment, if it is not already happening. He will be toxic. Having Livestrong on a resume will carry a dark cloud and provoke endless questions.. "Did you know what Lance had been doing all those years? Ever see him take drugs?"
For as high as he had risen, his fall will be as stark in contrast. Too much trust being betrayed. Too much emotional toll for the true believers. Too many lies for too many years. The math will be short form and obvious: He cheated. It won't be some complex financial scheme (Mozila) that most folks can't grasp, or some stock exchange crime, like Madoff or Milken. He will be a clear and obvious bad guy, with not one ounce of "hero" to show once it is all done. There is no redemption story here.
Really, it is a tragic ending for a guy who had it all. Had dream-like athletic accomplishments. Lived in a dream-like world and life, business, charity, wife(s) and kids, fans, real followers who'd adored him and would do anything for their one inspiration. It is these people who needed it to be real to get them through cancer or inspire them to fight when it was bleak. But it was a lie. And that lie will hurt all these people, more deeply than any lie I can recall in recent history, due to the personal-ness that so many feel in connection with him and his story and this being intertwined with the hope, faith and trust placed in him.