Dr. Kingsley Hampton spoke in the rider’s defence and said that he estimated Tiernan-Locke had a total alcohol intake in the evening of 335 grams, over 33 units of alcohol.
Per wiki, a unit of alcohol is 10 ml in Britain, but that is 7.9 grams. I hope the link got it wrong, that he consumed 335 ml, not grams, of alcohol. That would be the equivalent of three and a half bottles of wine. He did say he drank most of two bottles of wine, just as starters. (To put this in perspective for you beer drinkers, that would be about 5.5 liters of typical American beer, about sixteen 12 oz cans.)
If he really did consume 335 grams of alcohol, that is about 425 ml, or nearly five bottles of wine.
I’m pretty sure that would be a lethal dose for me, but YMMV.
An obvious problem with the dehydration defense is that while it would increase HT/Hb, it would also increase retics. In fact, since the ratio is important, plasma volume is mostly irrelevant, unless it can be shown to have some more indirect effect on the relevant cells. I understand he had a theory about that, too, but it's easy to see how he was grasping at straws.