There is also a small bump at the end of the stage to Rapolano Terme that was not there previously
And a slightly different end to the Perugia ITT
The TT finish is more of an uphill drag now while before it had a 2km at 9/10% climb so Pogačar is less likely to win this one.
The small bump on the road on stage 6 shouldn't make much of a difference unless its in a breakaway context.